Lianza Alessandro Cavalcanti, Diniz Maria de Fátima Rodrigues, Sawamura Karen Saori Shiraishi, Menezes Carolina da Rocha Brito, de Sousa Lobo Silva Isabela, Leal Gabriela Nunes
Echocardiography Laboratory, Instituto da Criança e do Adolescente do Hospital das Clínicas da Universidade de São Paulo São Paulo, Brazil.
Department of Paediatric and Foetal Echocardiography, Hospital do Coração de São Paulo São Paulo, Brazil.
Eur Cardiol. 2023 Jul 27;18:e47. doi: 10.15420/ecr.2023.15. eCollection 2023.
The most severe complication of Kawasaki disease, an inflammatory disorder of young children, is the formation of coronary artery aneurysms. It is known that patients with coronary artery aneurysms, particularly those with medium and large lesions, have a higher risk of future major cardiovascular events. In contrast, there is a lack of data on the cardiovascular status in long-term follow-up for Kawasaki disease patients without coronary involvement or with self-limited coronary artery aneurysms, resulting in most patients being discharged after 5 years. Even though some paediatricians may believe these patients should not be followed at all, studies indicating a dysfunctional endothelium show the need for further investigation. Consequently, a review of the most significant aspects of Kawasaki disease, and the necessity of correctly identifying, treating and monitoring these patients, particularly those with a higher risk of complications, was conducted.
川崎病是一种发生于幼儿的炎症性疾病，其最严重的并发症是冠状动脉瘤的形成。已知患有冠状动脉瘤的患者，尤其是那些有中大型病变的患者，未来发生重大心血管事件的风险更高。相比之下，对于无冠状动脉受累或有自限性冠状动脉瘤的川崎病患者，长期随访中的心血管状况缺乏数据，导致大多数患者在5年后出院。尽管一些儿科医生可能认为根本不应随访这些患者，但表明内皮功能障碍的研究显示有必要进一步调查。因此，对川崎病最重要的方面以及正确识别、治疗和监测这些患者，尤其是那些并发症风险较高患者的必要性进行了综述。
