Lee Hanall, Lee Joon Ho, Lee Tae Lee, Ko Do-Kyung, Kang Nyeonju
Department of Human Movement Science, Incheon National University, Incheon, Republic of Korea.
Neuromechanical Rehabilitation Research Laboratory, Incheon National University, Incheon, Republic of Korea.
Front Psychol. 2023 Jul 20;14:1211034. doi: 10.3389/fpsyg.2023.1211034. eCollection 2023.
Transcranial direct current stimulation (tDCS) is one of the non-invasive brain stimulation techniques that can improve motor functions. As bimanual motor actions require high motor cortical activations between hemispheres, applying bilateral anodal stimulation on left and right sides of primary motor cortex (M1) can improve for improvements in bimanual motor tasks. This study investigated which bilateral tDCS protocol effectively improves bimanual hand-grip force control capabilities in healthy young adults. We used three different bilateral tDCS protocols: (a) dual-anodal stimulation on the M1 of bilateral hemispheres (Bi-AA), (b) anodal-cathodal stimulation on the M1 of dominant and nondominant hemispheres (Bi-AC), and (c) sham stimulation (Sham). The results indicated that applying the Bi-AA significantly improved bilateral motor synergies estimated by uncontrolled manifold analysis relative to Sham. However, these differences were not observed in the comparison between Bi-AA and Bi-AC as well as between Bi-AC and Sham. These findings suggest that facilitating motor cortical activations between both hemispheres may be an additional option for advancing interlimb motor coordination patterns.
经颅直流电刺激（tDCS）是一种可改善运动功能的非侵入性脑刺激技术。由于双手运动动作需要半球间较高的运动皮层激活，在初级运动皮层（M1）的左右两侧施加双侧阳极刺激可改善双手运动任务。本研究调查了哪种双侧tDCS方案能有效提高健康年轻人的双手握力控制能力。我们使用了三种不同的双侧tDCS方案：（a）双侧半球M1的双阳极刺激（Bi-AA），（b）优势半球和非优势半球M1的阳极-阴极刺激（Bi-AC），以及（c）假刺激（Sham）。结果表明，与假刺激相比，应用Bi-AA通过非受控流形分析估计可显著改善双侧运动协同作用。然而，在Bi-AA与Bi-AC之间以及Bi-AC与假刺激之间的比较中未观察到这些差异。这些发现表明，促进双侧半球之间的运动皮层激活可能是推进肢体间运动协调模式的另一种选择。
