Yamaguchi Yoshitaka, Takada Tatsuro, Uchida Kazuki, Miyata Kei, Kurisu Kota, Okuyama Tomohiro, Tomeoka Fumiki, Ajiki Minoru, Hokari Masaaki, Asaoka Katsuyuki
Department of Cerebrovascular Medicine, Teine Keijinkai Hospital, Sapporo, Hokkaido, Japan.
Department of Neurosurgery, Teine Keijinkai Hospital, Sapporo, Hokkaido, Japan.
J Neuroendovasc Ther. 2023;17(5):101-106. doi: 10.5797/jnet.cr.2023-0003. Epub 2023 Apr 19.
Recent studies evaluating plaque protrusion at carotid artery stenting (CAS) using optical coherence tomography showed not a few cases of plaque protrusion when using double-layer micromesh stents. We report a case of symptomatic internal carotid artery (ICA) stenosis with at-risk unstable plaques in which CAS was successfully performed using a stent-in-stent technique by the combined use of a closed-cell stent and a dual-layer micromesh stent.
An 87-year-old Japanese man with dysarthria and right hemiparesis was diagnosed with atheromatous cerebral embolism caused by severe left ICA stenosis on MRI and DSA. MRI with T1-weighted black blood methods showed high intensities in the plaques of the left ICA, suggesting unstable plaque characteristics with intraplaque hemorrhage components. On day 20, CAS was performed. After the pre-stent dilation under proximal and distal protection, a Carotid WALLSTENT was placed to cover the stenotic lesion. Then, a CASPER Rx was placed from the proximal left ICA to the common carotid artery to cover the Carotid WALLSTENT. Although visible plaque debris was recognized in the aspirated blood, the debris became invisible after aspiration of 1300 mL. Postoperative angiography showed enough dilation of the left ICA, with no plaque protrusion or acute stent thrombosis. The patient had an uneventful postoperative course and was discharged without any neurological sequelae.
The present case suggests that the combined stent-in-stent technique using a closed-cell stent and a micromesh stent can be considered as one of the treatment strategies for preventing plaque protrusion and procedural ischemic complications in patients with high-risk carotid plaques.
近期利用光学相干断层扫描评估颈动脉支架置入术(CAS)时斑块突出情况的研究显示,使用双层微网眼支架时存在不少斑块突出的病例。我们报告一例有症状的颈内动脉(ICA)狭窄合并高危不稳定斑块的病例,该病例通过联合使用闭孔支架和双层微网眼支架采用支架套支架技术成功实施了CAS。
一名87岁日本男性,出现构音障碍和右侧偏瘫,经MRI和DSA诊断为严重左侧ICA狭窄所致的动脉粥样硬化性脑栓塞。采用T1加权黑血法的MRI显示左侧ICA斑块呈高强度信号,提示斑块具有不稳定特征且含有斑块内出血成分。在第20天实施了CAS。在近端和远端保护下进行预支架扩张后,置入一枚颈动脉WALLSTENT以覆盖狭窄病变。然后,从左侧ICA近端至颈总动脉置入一枚CASPER Rx以覆盖颈动脉WALLSTENT。尽管在抽吸的血液中可见斑块碎片,但在抽吸1300 mL后碎片变得不可见。术后血管造影显示左侧ICA充分扩张,无斑块突出或急性支架血栓形成。患者术后恢复顺利,出院时无任何神经后遗症。
本病例提示,联合使用闭孔支架和微网眼支架的支架套支架技术可被视为预防高危颈动脉斑块患者斑块突出和手术缺血性并发症的治疗策略之一。