Hegland Pål André, Kolotkin Ronette L, Andersen John Roger
Faculty of Health and Social Sciences, Western Norway University of Applied Sciences, Førde, Norway.
Department of Family Medicine and Community Health, Duke University School of Medicine, Durham, NC, USA.
Patient Relat Outcome Meas. 2023 Aug 1;14:235-241. doi: 10.2147/PROM.S414144. eCollection 2023.
Many patients seeking bariatric surgery experience reduced health-related quality of life (HRQOL). A simple clinical tool, the Patient-Reported Outcomes in Obesity (PROS), was developed to address patients' HRQOL concerns during clinical consultations and facilitate meaningful dialogue. The present study aims to explore its sensitivity to change.
A prospective study of patients undergoing bariatric surgery was conducted. The patients responded to items on the PROS and the Obesity-related Problems Scale (OP) before surgery and three, 12 and 24 months after surgery. Longitudinal mixed-effects models were applied to estimate the change in PROS and OP scores over time.
Thirty-eight patients were included. A significant change over time was detected for the PROS with the largest effect size at 24 months (effect size -1.34, p ˂ 0.001), while the corresponding effect size for the OP was -1.32 (p ˂ 0.001). In all items of the PROS, the majority of patients responded not bothered at 24 months. The items physical activity, pain, sleep and self-esteem showed the largest change in the percentage of patients reporting not bothered from baseline to 24 months after surgery.
The PROS is sensitive to change over time and may be used as a brief, easy to administer tool to facilitate a conversation about obesity-specific quality of life in clinical consultations.
许多寻求减肥手术的患者健康相关生活质量（HRQOL）下降。开发了一种简单的临床工具——肥胖患者报告结局（PROS），以解决临床会诊期间患者对健康相关生活质量的担忧，并促进有意义的对话。本研究旨在探讨其对变化的敏感性。
对接受减肥手术的患者进行了一项前瞻性研究。患者在手术前以及手术后3个月、12个月和24个月对PROS和肥胖相关问题量表（OP）上的项目进行了回答。应用纵向混合效应模型来估计PROS和OP评分随时间的变化。
纳入了38名患者。检测到PROS随时间有显著变化，在24个月时效应量最大（效应量为-1.34，p＜0.001），而OP的相应效应量为-1.32（p＜0.001）。在PROS的所有项目中，大多数患者在24个月时表示没有困扰。从基线到术后24个月，报告没有困扰的患者百分比变化最大的项目是身体活动、疼痛、睡眠和自尊。
PROS对随时间的变化敏感，可作为一种简短、易于管理的工具，在临床会诊中促进关于肥胖特定生活质量的对话。
