Ogawa M
Gan To Kagaku Ryoho. 1986 May;13(5):1829-36.
Among new drugs being studied currently, AMSA and mitoxantrone have shown significant usefulness against acute non-lymphocytic leukemia in adults. Remission induction therapy consisting of daunomycin and cytosine arabinoside has been commonly selected as the first line of treatment and the complete remission rate obtained has exceeded 70%. Postremission therapy consolidation has been judged to be necessary while the clinical roles of maintenance and intensification remain to be clarified and appear to still require an investigational approach.
在目前正在研究的新药中,胺苯吖啶和米托蒽醌已显示出对成人急性非淋巴细胞白血病有显著疗效。由柔红霉素和阿糖胞苷组成的缓解诱导疗法通常被选为一线治疗方法,所获得的完全缓解率已超过70%。缓解后治疗巩固被认为是必要的,而维持和强化的临床作用仍有待阐明,似乎仍需要采用研究性方法。