Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Front Endocrinol (Lausanne). 2023 Jul 20;14:1212878. doi: 10.3389/fendo.2023.1212878. eCollection 2023.
Our aim was to evaluate the association between midday napping, combined sleep quality, and insulin resistance surrogates and the risk of hypertension in patients with type 2 diabetes mellitus (T2DM).
Data were collected using a standardized questionnaire. Binary logistic regression was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) for the risk of hypertension. Systolic and diastolic blood pressure were grouped as categorical variables and unpaired two-sided Student's t-test and Spearman correlation analysis were performed to estimate the association between different blood pressure levels and insulin resistance surrogates.
The overall prevalence rate of hypertension was 50%. Age (OR = 1.056, 95% CI:1.044-1.068), poor sleep quality (OR = 1.959, 95% CI:1.393-2.755), hyperlipidemia (OR = 1.821, 95% CI:1.462-2.369), family history of hypertension (OR = 2.811, 95% CI:2.261-3.495), and obesity (OR = 5.515, 95% CI:1.384-21.971) were significantly associated with an increased risk of hypertension. Midday napping for 1-30 min was negatively correlated with the risk of hypertension (OR = 0.534, 95% CI:0.305-0.936, P <0.05).
Poor sleep quality and obesity are independent risk factors for hypertension. Midday napping (1-30 min) is associated with a decreased risk of hypertension in patients with T2DM.
评估午睡、综合睡眠质量与胰岛素抵抗指标与 2 型糖尿病（T2DM）患者高血压风险之间的关联。
采用标准化问卷收集数据。采用二元逻辑回归估计高血压风险的比值比（OR）和 95%置信区间（CI）。将收缩压和舒张压分组为分类变量，并进行非配对双侧 Student's t 检验和 Spearman 相关分析，以评估不同血压水平与胰岛素抵抗指标之间的关系。
高血压的总患病率为 50%。年龄（OR=1.056，95%CI：1.044-1.068）、睡眠质量差（OR=1.959，95%CI：1.393-2.755）、血脂异常（OR=1.821，95%CI：1.462-2.369）、高血压家族史（OR=2.811，95%CI：2.261-3.495）和肥胖（OR=5.515，95%CI：1.384-21.971）与高血压风险增加显著相关。午睡 1-30 分钟与高血压风险呈负相关（OR=0.534，95%CI：0.305-0.936，P<0.05）。
睡眠质量差和肥胖是高血压的独立危险因素。午睡（1-30 分钟）与 T2DM 患者的高血压风险降低相关。
