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绝经后女性睡眠时间和日间小睡与2型糖尿病患病率的种族特异性关联

Ethnic-specific associations of sleep duration and daytime napping with prevalent type 2 diabetes in postmenopausal women.

作者信息

Shadyab Aladdin H, Kritz-Silverstein Donna, Laughlin Gail A, Wooten Wilma J, Barrett-Connor Elizabeth, Araneta Maria Rosario G

机构信息

San Diego State University/University of California, San Diego Joint Doctoral Program in Public Health (Epidemiology), CA, United States; Graduate School of Public Health, San Diego State University, Hardy Tower Room 119, 5500 Campanile Drive, San Diego, CA 92182-4162, United States.

Department of Family Medicine and Public Health, School of Medicine, University of California, San Diego, 9500 Gilman Drive, Mail code: 0607, La Jolla, CA 92093-0607, United States.

出版信息

Sleep Med. 2015 Feb;16(2):243-9. doi: 10.1016/j.sleep.2014.11.010. Epub 2014 Dec 12.

Abstract

OBJECTIVE

The objective of this study was to evaluate ethnic differences in the associations of nighttime sleep and daytime napping durations with prevalent type 2 diabetes.

METHODS

Samples of White (n = 908), Filipina (n = 330), and Black (n = 371) community-dwelling, postmenopausal women aged 50-86 years were evaluated with cross-sectional data obtained during 1992-1999 including self-reported duration of nighttime sleep and daytime napping, behaviors, medical history, and medication use. The prevalence of type 2 diabetes was evaluated with a 2-h 75-g oral glucose tolerance test.

RESULTS

Overall, 10.9% of White, 37.8% of Filipina, and 17.8% of Black women had type 2 diabetes. Average sleep durations were 7.3, 6.3, and 6.6 h and napping durations were 16.8, 31.7, and 25.9 min for White, Filipina, and Black women, respectively. Sleep duration showed a significant (p < 0.01) nonlinear association with type 2 diabetes in Filipina women, with increased odds of diabetes at both low and high sleep durations independent of age, body mass index (BMI), triglyceride to high-density lipoprotein (HDL) ratio, hypertension, and daytime napping duration. Daytime napping duration was associated with type 2 diabetes only among White women; those napping ≥ 30 min/day had 74% (95% confidence interval (CI) = 10%, 175%) higher odds of diabetes compared to non-nappers independent of covariates including nighttime sleep duration.

CONCLUSIONS

Results suggest ethnic-specific associations of nighttime sleep and daytime napping durations with type 2 diabetes.

摘要

目的

本研究的目的是评估夜间睡眠时长和白天小睡时长与2型糖尿病患病率之间的种族差异。

方法

对年龄在50 - 86岁的908名白人、330名菲律宾裔和371名黑人社区绝经后女性样本进行评估,数据来自1992 - 1999年期间的横断面调查,包括自我报告的夜间睡眠和白天小睡时长、行为、病史及用药情况。通过2小时75克口服葡萄糖耐量试验评估2型糖尿病的患病率。

结果

总体而言,10.9%的白人、37.8%的菲律宾裔和17.8%的黑人女性患有2型糖尿病。白人、菲律宾裔和黑人女性的平均睡眠时间分别为7.3小时、6.3小时和6.6小时,平均小睡时长分别为16.8分钟、31.7分钟和25.9分钟。在菲律宾裔女性中,睡眠时间与2型糖尿病呈显著(p < 0.01)非线性关联,无论年龄、体重指数(BMI)、甘油三酯与高密度脂蛋白(HDL)比值、高血压及白天小睡时长如何,睡眠时长过短或过长时患糖尿病的几率均会增加。仅在白人女性中,白天小睡时长与2型糖尿病有关;与不午睡者相比,每天午睡≥30分钟的女性患糖尿病的几率高74%(95%置信区间(CI)= 10%,175%),且不受包括夜间睡眠时间在内的协变量影响。

结论

结果表明夜间睡眠和白天小睡时长与2型糖尿病之间存在种族特异性关联。

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