Kooshesh Leila, Nateghian Zohre, Aliabadi Elham
Department of Genetics, Fars Academic Center for Education, Culture and Research, ACECR, Shiraz, Iran.
Islamic Azad University of Isfahan (Khorasgan) Branch, Isfahan, Iran.
J Reprod Infertil. 2023 Apr-Jun;24(2):69-84. doi: 10.18502/jri.v24i2.12491.
L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A literature search was performed using PubMed (including Medline) from the database earliest inception to 2021. Eligibility criteria included studies on protective effects of L-carnitine against damages to the male reproductive system. Based on the findings of the current study, L-carnitine has an effective potential to protect testis and improve conventional and functional sperm parameters against ROS-induced damages by sperm cryopreservation, busulfan treatment, and radiation.
左旋肉碱凭借其抗氧化潜能，在减少男性生殖道活性氧生成方面发挥着重要作用；因此，通过左旋肉碱治疗可观察到精子发生过程以及精浆中精子结构和功能参数的显著改善。使用PubMed（包括Medline）从数据库建立之初至2021年进行了文献检索。纳入标准包括关于左旋肉碱对男性生殖系统损伤保护作用的研究。基于本研究结果，左旋肉碱具有有效潜能来保护睾丸，并改善常规和功能性精子参数，以抵御精子冷冻保存、白消安治疗及辐射所诱导的活性氧损伤。
