Lopes Samuel Oliveira, Gonçalves Ana Raquel, Macedo Guilherme, Santos-Antunes João
Faculty of Medicine, University of Porto, Porto, Portugal.
Gastroenterology Department, Centro Hospitalar Universitário S. João, Porto, Portugal.
Porto Biomed J. 2023 Aug 3;8(4):e226. doi: 10.1097/j.pbj.0000000000000226. eCollection 2023 Jul-Aug.
Gastroesophageal reflux disease (GERD) is a common chronic disease that affects one-third of the population worldwide. In recent years, there have been significant advances for diagnostic workup, which leads to better identification of reflux-related complications. Classically, the mainstay of therapy has been proton pump inhibitor and lifestyle and dietary modifications. For refractory GERD the gold-standard therapies are surgical antireflux procedures. Recently, endoscopic procedures have emerged as safe and efficient alternatives to surgery. These could represent a less invasive approach, with scarce morbidity and with a well-tolerated profile. Each of the existing endoscopic techniques for the treatment of GERD are addressed in this report, highlighting their potential advantages, aiming at helping decide the best management of these patients. Future studies, with larger numbers of patients, may allow a definitive role for these techniques in the management of GERD to be established.
胃食管反流病（GERD）是一种常见的慢性疾病，影响着全球三分之一的人口。近年来，诊断检查取得了重大进展，这有助于更好地识别反流相关并发症。传统上，治疗的主要方法是使用质子泵抑制剂以及改变生活方式和饮食习惯。对于难治性GERD，金标准治疗方法是抗反流手术。最近，内镜手术已成为手术的安全有效替代方案。这些方法可能代表一种侵入性较小的方法，发病率低且耐受性良好。本报告讨论了现有的每种用于治疗GERD的内镜技术，突出了它们的潜在优势，旨在帮助确定这些患者的最佳治疗方案。未来针对更多患者的研究可能会确定这些技术在GERD治疗中的明确作用。
