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低强度体外冲击波疗法(LI-ESWT)对勃起功能障碍患者的疗效

Efficacy of Low-Intensity Extra Corporal Shockwave Therapy (LI-ESWT) in Patients With Erectile Dysfunction.

作者信息

Islam Rayhan, Rahaman Khandakar Shafiur, Hawlader Mohammad Delwer Hossain

机构信息

School of Health & Life Sciences, North South University, Dhaka, Bangladesh.

RANAS Ltd. - Spin-off of Eawag, Zurich, Switzerland.

出版信息

J Family Reprod Health. 2023 Jun;17(2):93-99. doi: 10.18502/jfrh.v17i2.12872.

Abstract

OBJECTIVE

Erectile dysfunction (ED) is a common cause of sexual disorders in men with limited treatment options. This study aimed to determine the efficacy of low-intensity extra corporal shockwave therapy (LI-ESWT) in patients suffering from ED.

MATERIALS AND METHODS

A single-group, pre-test, and post-test pre-experimental study were conducted. Thirty-one ED patients were prospectively selected according to the eligibility criteria. In each session, 3000 shocks were applied at 5 points over the penis. Eight sessions were delivered in total with a 2-3-day interval. The patient's condition was assessed using the International Index of Electric Function (IIEF-5) questionnaire at baseline and one month after the last treatment session. Paired t-test was used to determine the difference between the pre-test and post-test.

RESULTS

Mean age of the patients was 44.6 (± 14.70) ranging from 25 to 78 years. The majority of them were married (83.9%) and service providers (51.6%). We have also found 51.6% overweight, 9.7% obese, 48.4% diabetic, 45.2% hypertensive, 12.9% with enlarged prostate, 45.2% smoker, 25.8% alcoholic, and 71% with sleep disturbances. During the pre-test, 9.7% had severe ED and 51.6% had moderate ED. After the treatment, no patients were found with severe ED, and few of them had moderate ED (9.7%). The mean difference in IIEF-5 score during the pre-test and post-test was statistically significant (p= < 0.001).

CONCLUSION

The study showed efficacy of LI-ESWT in a subset of patients with ED. Future studies with larger sample size, placebo group, and longer follow-up periods are recommended.

摘要

目的

勃起功能障碍(ED)是男性性功能障碍的常见原因,治疗选择有限。本研究旨在确定低强度体外冲击波疗法(LI-ESWT)对ED患者的疗效。

材料与方法

进行了一项单组、预测试和后测试的实验前研究。根据纳入标准前瞻性选择了31例ED患者。每次治疗时,在阴茎上的5个点施加3000次冲击波。共进行8次治疗,间隔2-3天。在基线和最后一次治疗后1个月,使用国际勃起功能指数(IIEF-5)问卷评估患者状况。采用配对t检验确定测试前和测试后的差异。

结果

患者的平均年龄为44.6(±14.70)岁,年龄范围为25至78岁。他们中的大多数已婚(83.9%),职业为服务行业(51.6%)。我们还发现51.6%超重,9.7%肥胖,48.4%患有糖尿病,45.2%患有高血压,12.9%前列腺肿大,45.2%吸烟,25.8%饮酒,71%有睡眠障碍。测试前,9.7%患有重度ED,51.6%患有中度ED。治疗后,未发现重度ED患者,只有少数患者患有中度ED(9.7%)。测试前和测试后IIEF-5评分的平均差异具有统计学意义(p = <0.001)。

结论

该研究表明LI-ESWT对一部分ED患者有效。建议未来进行更大样本量、设置安慰剂组和更长随访期的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2af8/10397529/732dd3e2b28a/JFRH-17-93-g001.jpg

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