Sinha Ruchita, Datta Mamta Rath, Singh Vinita
Department of Obs & Gynae, Tata Manipal Medical College, Jharkhand, India.
Department of Obs & Gynae, Tata Main Hospital, Jharkhand, India.
J Family Reprod Health. 2023 Jun;17(2):105-108. doi: 10.18502/jfrh.v17i2.12874.
Dengue cases in pregnancy have high morbidity and mortality. More so if it leads to immune thrombocytopenic purpura which causes a drastic decrease in platelet, increasing chances of bleeding and mortality and pregnancy itself being a state of hemodynamic instability.
Here, we present a case of dengue causing secondary immune thrombocytopenia. Managing these cases is challenging and need a multidisciplinary approach and should be done at a higher center. In previous reports, thrombocytopenia in such cases responded to steroids or IVIG. But in our case patient did not respond to either of them but to Romiplostim. There are only a few studies on the use of Romiplostim in dengue and dengue induced ITP and more study is required.
Dengue induced persistent thrombocytopenia is rare but should always be kept in mind in managing these cases.
妊娠期登革热病例具有较高的发病率和死亡率。如果导致免疫性血小板减少性紫癜，情况更是如此，这会导致血小板急剧减少，增加出血和死亡的几率，而且妊娠本身就是一种血流动力学不稳定的状态。
在此，我们呈现一例登革热导致继发性免疫性血小板减少的病例。处理这些病例具有挑战性，需要多学科方法，且应在上级中心进行。在以往的报告中，此类病例的血小板减少对类固醇或静脉注射免疫球蛋白有反应。但在我们的病例中，患者对这两种治疗均无反应，却对罗米司亭有反应。关于罗米司亭在登革热及登革热诱发的免疫性血小板减少症中的应用，仅有少数研究，还需要更多研究。
登革热诱发的持续性血小板减少症较为罕见，但在处理这些病例时应始终予以考虑。
