四元杂环的应变与复杂性、Passerini反应和Ugi反应以及TOSMIC产物的进一步衍生化
Strain and Complexity, Passerini and Ugi Reactions of Four-Membered Heterocycles and Further Elaboration of TOSMIC Product.
作者信息
Sztanó Gábor, Dobi Zoltán, Soós Tibor
机构信息
Institute of Organic Chemistry, Research Centre for Natural Sciences, Budapest, 1519, Hungary.
Hevesy György PhD School of Chemistry, ELTE Eötvös Loránd University, Budapest, 1117, Pázmány Péter sétány 1/A, Hungary.
出版信息
ChemistryOpen. 2023 Aug;12(8):e202200083. doi: 10.1002/open.202200083.
Abstract
Straightforward and general Passerini and Ugi procedures have been developed to incorporate four-membered heterocycles into highly functionalized scaffolds. Additionally, toslymethyl isocyanide (TosMIC)-derived Ugi adducts have been prepared, showcasing the prospect of the multicomponent reaction.
摘要
已经开发出直接且通用的帕塞里尼反应和乌吉反应，以便将四元杂环纳入高度官能化的支架中。此外，还制备了源自对甲苯磺酰甲基异腈（TosMIC）的乌吉加合物，展示了多组分反应的前景。
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