位于蝶眶骨和脑桥的朗格汉斯细胞组织细胞增多症：病例说明
Langerhans cell histiocytosis located in the spheno-orbital bone and the pons: illustrative case.
作者信息
Cekic Efecan, Karagoz Ahmet, Sakar Mustafa, Senay Rabia Emel, Akar Kadriye Ebru, Bozkurt Suheyla, Dagcinar Adnan
机构信息
Departments of1Neurosurgery.
2Pediatric Hematology and Oncology Diseases, and.
出版信息
J Neurosurg Case Lessons. 2023 Jul 31;6(5). doi: 10.3171/CASE22367.
BACKGROUND
This is a case of aggressive Langerhans cell histiocytosis (LCH) with an atypical intracranial location.
OBSERVATIONS
In this report, the authors present the diagnosis and treatment of a 12-year-old male patient diagnosed with LCH. The patient was admitted to the emergency department with left-sided facial palsy, and a solid lesion with mass effect in the pons was found. A biopsy was performed via suboccipital craniotomy, and the diagnosis was LCH. A chemotherapy regimen was started since the LCH sample was the resistant type. The patient showed improvement in his neurological deficit following treatment.
LESSONS
This rare localized and aggressive case's diagnosis process and treatment choices may apply to future cases.
背景
这是一例具有非典型颅内定位的侵袭性朗格汉斯细胞组织细胞增多症（LCH）病例。
观察结果
在本报告中，作者介绍了一名被诊断为LCH的12岁男性患者的诊断和治疗情况。该患者因左侧面神经麻痹入住急诊科，发现脑桥有一个具有占位效应的实性病变。通过枕下开颅术进行了活检，诊断为LCH。由于LCH样本为耐药型，因此开始了化疗方案。治疗后患者的神经功能缺损有所改善。
经验教训
这个罕见的局限性侵袭性病例的诊断过程和治疗选择可能适用于未来的病例。
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