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在美国学术医疗体系中,针对经验丰富的患者实施并评估华法林患者自我管理(PSM)计划。

Implementation and evaluation of a warfarin patient self-management (PSM) program among experienced patients in a U.S. academic health system.

机构信息

University of Utah Health Thrombosis Service, Salt Lake City, UT, USA.

Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, UT, USA.

出版信息

J Thromb Thrombolysis. 2023 Nov;56(4):511-513. doi: 10.1007/s11239-023-02877-9. Epub 2023 Aug 7.

DOI:10.1007/s11239-023-02877-9
Abstract

Warfarin patient self-management (PSM) is when a patient independently manages their warfarin therapy using a decision-support tool provided by their anticoagulation provider. Clinical trials of PSM, conducted predominantly in Europe, have consistently demonstrated superior efficacy without compromising safety. However, the evidence-based practice of PSM is rarely utilized in the United States (U.S.). We describe initiatives completed to implement a successful PSM program among experienced warfarin-taking patients in a U.S. academic health system by overcoming perceived barriers. The results showed PSM resulted in similar or improved INR control, and an estimated 68% reduction in pharmacist workload.

摘要

华法林患者自我管理(PSM)是指患者使用抗凝提供者提供的决策支持工具独立管理其华法林治疗。PSM 的临床试验主要在欧洲进行,一致证明其在不影响安全性的情况下具有更好的疗效。然而,在美国(美国),很少有基于证据的 PSM 实践。我们描述了为克服感知障碍,在美国学术医疗系统中为经验丰富的华法林服用患者实施成功的 PSM 计划所完成的举措。结果表明,PSM 可实现相似或改善的 INR 控制,估计可减少 68%的药剂师工作量。

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引用本文的文献

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medRxiv. 2025 Aug 21:2025.08.18.25333912. doi: 10.1101/2025.08.18.25333912.
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A qualitative study exploring patient experiences and opinions of warfarin patient self-management in the US healthcare system.一项探索美国医疗保健系统中患者对华法林自我管理的体验和看法的定性研究。
J Am Coll Clin Pharm. 2024 Mar;7(3):198-206. doi: 10.1002/jac5.1912. Epub 2023 Dec 19.
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Comparative effectiveness of warfarin management strategies: a systematic review and network meta-analysis.

本文引用的文献

1
Clinical Outcomes of Different Warfarin Self-Care Strategies: A Systematic Review and Network Meta-Analysis.不同华法林自我管理策略的临床结局:系统评价和网络荟萃分析。
Thromb Haemost. 2022 Apr;122(4):492-505. doi: 10.1055/a-1677-9608. Epub 2022 Jan 20.
2
American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy.美国血液学会 2018 年静脉血栓栓塞症管理指南:抗凝治疗的最佳管理。
Blood Adv. 2018 Nov 27;2(22):3257-3291. doi: 10.1182/bloodadvances.2018024893.
3
Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report.
华法林管理策略的比较效果:一项系统评价和网状Meta分析
EClinicalMedicine. 2024 Jul 2;74:102712. doi: 10.1016/j.eclinm.2024.102712. eCollection 2024 Aug.
抗栓治疗心房颤动:CHEST 指南和专家报告。
Chest. 2018 Nov;154(5):1121-1201. doi: 10.1016/j.chest.2018.07.040. Epub 2018 Aug 22.