Wilson Aaron S, Slager Stacey, Jones Aubrey E, Vazquez Sara R, Barnes Geoffrey D, Sylvester Katelyn, Chan Linh, Ragheb Bishoy, Witt Daniel M
University of Utah College of Pharmacy, Salt Lake City, Utah, USA.
University of Utah Health Thrombosis Service, Salt Lake City, Utah, USA.
J Am Coll Clin Pharm. 2024 Mar;7(3):198-206. doi: 10.1002/jac5.1912. Epub 2023 Dec 19.
Despite consensus guideline recommendations, the use of warfarin patient self-management (PSM) in the United States (US) healthcare system remains underutilized.
To gain an understanding of the barriers and facilitators to warfarin PSM in US healthcare systems through qualitative exploration of the opinions of select US patients receiving warfarin therapy.
Individual patient interviews were conducted at five geographically diverse sites. Grounded theory analysis was performed on interview transcriptions using the consolidated framework for implementation research (CFIR) to identify facilitators and barriers to PSM implementation within the US healthcare system.
A total of 40 patients were interviewed. Four major themes emerged from the interviews: (1) "Patients are resourceful problem solvers who know themselves better than clinicians" (CFIR domain "Characteristics of Individuals"); (2) The provider-patient relationship is key to successful PSM (CFIR domains "Inner Setting" and "Intervention Characteristics"); (3) Patients are willing and interested in trying PSM if not already doing so (CFIR domains "Process," "Intervention Characteristics," "Inner Setting, and "Characteristics of Individuals"); and (4) Point-of-care international normalized ratio (INR) monitoring is an important PSM facilitator (CFIR "Intervention Characteristics," "Outer Setting," "Inner Setting," and "Process" domains).
Interview participants were willing and interested in trying PSM. Core elements of warfarin PSM include timely access to INR results, and a framework to support PSM decision making. Home INR monitoring is likely ideal for facilitating PSM implementation as is maintaining strong provider-patient relationships where providers, including clinical pharmacists, trust their patients and act as a safety net for PSM decision making.
尽管有共识性指南建议,但在美国医疗保健系统中,华法林患者自我管理(PSM)的使用仍未得到充分利用。
通过对部分接受华法林治疗的美国患者的意见进行定性探索,了解美国医疗保健系统中华法林PSM的障碍和促进因素。
在五个地理位置不同的地点进行了个体患者访谈。使用实施研究综合框架(CFIR)对访谈记录进行扎根理论分析,以确定美国医疗保健系统中PSM实施的促进因素和障碍。
共访谈了40名患者。访谈中出现了四个主要主题:(1)“患者是足智多谋的问题解决者,他们比临床医生更了解自己”(CFIR领域“个体特征”);(2)医患关系是PSM成功的关键(CFIR领域“内部环境”和“干预特征”);(3)如果尚未尝试,患者愿意并对尝试PSM感兴趣(CFIR领域“过程”、“干预特征”、“内部环境”和“个体特征”);(4)即时国际标准化比值(INR)监测是PSM的重要促进因素(CFIR“干预特征”、“外部环境”、“内部环境”和“过程”领域)。
访谈参与者愿意并对尝试PSM感兴趣。华法林PSM的核心要素包括及时获取INR结果,以及支持PSM决策的框架。家庭INR监测可能是促进PSM实施的理想方式,保持强大的医患关系也是如此,在这种关系中,包括临床药师在内的医疗服务提供者信任他们的患者,并作为PSM决策的安全网。