Doostkam Aida, Malekmakan Leila, Hosseinpour Alireza, Janfeshan Sahar, Roozbeh Jamshid, Masjedi Fatemeh
Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz 7193635899, Iran.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134853185, Iran.
Asian Biomed (Res Rev News). 2022 Aug 31;16(4):153-167. doi: 10.2478/abm-2022-0020. eCollection 2022 Aug.
This broad, narrative review highlights the roles of sialic acids as acidic sugars found on cellular membranes. The role of sialic acids in cellular communication and development has been well established. Recently, attention has turned to the fundamental role of sialic acids in many diseases, including viral infections, cardiovascular diseases, neurological disorders, diabetic nephropathy, and malignancies. Sialic acid may be a target for developing new drugs to treat various cancers and inflammatory processes. We recommend the routine measurement of serum sialic acid as a sensitive inflammatory marker in various diseases.
这篇内容广泛的叙述性综述强调了唾液酸作为细胞膜上发现的酸性糖的作用。唾液酸在细胞通讯和发育中的作用已得到充分证实。最近，人们的注意力已转向唾液酸在许多疾病中的基本作用，包括病毒感染、心血管疾病、神经障碍、糖尿病肾病和恶性肿瘤。唾液酸可能是开发治疗各种癌症和炎症过程新药的靶点。我们建议将血清唾液酸的常规检测作为各种疾病中一种敏感的炎症标志物。
