Cine Hidayet Safak, Uysal Ece, Senturk Salim, Ay Gülnihal, Caner Basak
Neurosurgery, Istanbul Medeniyet University, Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, TUR.
Neurological Surgery, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, TUR.
Cureus. 2023 Aug 6;15(8):e43032. doi: 10.7759/cureus.43032. eCollection 2023 Aug.
Epithelioid hemangioendothelioma is a rare mesenchymal tumor of vascular endothelial origin. Non-soft tissue epithelioid hemangioendothelioma can also be seen in different organs. Although chemotherapy has been used in some patients, complete surgical removal of the tumor tissue has proven to be the most durable solution. A 15-year-old female patient was admitted to our institution with right arm and neck pain. The patient complained of numbness and weakness in the right hand. Computerized tomography indicated an expansile lesion exhibiting osteolytic features located predominantly on the right side of the corpus, pedicle, lamina, and lateral processes of the C7-T1 vertebra. The patient underwent a surgical procedure involving the application of a bilateral C4-5-6 lateral mass screw, left C7-T1 pedicle screw, and bilateral T2-3 pedicle screw and fusion. The complete residual neoplasm was surgically removed during the procedure. Due to the rarity of epithelioid hemangioendothelioma, the existing literature on this topic is confined to case reports, supplemented by a small number of retrospective descriptive case series that aimed to improve our understanding of the clinical, pathological, and molecular features of the condition, as well as to guide potential treatment strategies.
上皮样血管内皮瘤是一种罕见的起源于血管内皮的间叶性肿瘤。非软组织上皮样血管内皮瘤也可见于不同器官。尽管一些患者使用了化疗，但事实证明，完整切除肿瘤组织是最持久的解决方案。一名15岁女性患者因右臂和颈部疼痛入住我院。患者主诉右手麻木和无力。计算机断层扫描显示一个膨胀性病变，主要位于C7-T1椎体的体部、椎弓根、椎板和横突右侧，具有溶骨性特征。患者接受了一项手术，包括应用双侧C4-5-6侧块螺钉、左侧C7-T1椎弓根螺钉和双侧T2-3椎弓根螺钉并进行融合。术中完整切除了残留肿瘤。由于上皮样血管内皮瘤罕见，关于该主题的现有文献仅限于病例报告，并辅以少量回顾性描述性病例系列，旨在增进我们对该病临床、病理和分子特征的理解，并指导潜在的治疗策略。
