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继发于骨化性骨纤维异常增殖症的感染的外科治疗。

Surgical Management of Infection Secondary to Cemento-osseous Dysplasia.

机构信息

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology South Avenue Zhongguancun, Haidian District, Beijing, PR China.

Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing China.

出版信息

J Craniofac Surg. 2023 Sep 1;34(6):e614-e617. doi: 10.1097/SCS.0000000000009556. Epub 2023 Aug 7.

Abstract

Cemento-osseous dysplasia (COD) of the jaws generally has no clinical manifestations when asymptomatic, thus requiring no treatment. However, secondary infection in COD requires surgical intervention. This study was focused on the evaluation of the surgical treatment of COD patients with secondary infections. The clinical data of COD patients with secondary infections, treated at the Peking University, Hospital of Stomatology between March 2021 and June 2022, were retrospectively reviewed. The data included age, sex, lesion characteristics, number of surgeries, and surgical outcomes. Seven COD patients with secondary infections underwent curettage, and the wounds were repaired using local soft tissue flaps, such as the buccal fat pad. Four of the patients had primary wound healing, while 3 presented with wound dehiscence. Healing occurred in 2 of these 3 patients after ~1 month of dressings. The remaining patient showed no improvement after 9 weeks, and underwent a second surgery, which led to primary wound healing. In conclusion, secondary infection in COD is an indication for surgical intervention, which may arrest the disease progression.

摘要

颌骨骨-牙性骨发育异常(COD)在无症状时通常无临床表现,因此无需治疗。然而,COD 的继发感染需要手术干预。本研究旨在评估继发感染的 COD 患者的手术治疗效果。回顾性分析 2021 年 3 月至 2022 年 6 月在北京大学口腔医院接受治疗的继发感染的 COD 患者的临床资料。资料包括年龄、性别、病变特征、手术次数和手术结果。7 例继发感染的 COD 患者行刮治术,采用颊脂垫等局部软组织瓣修复创面。4 例患者一期愈合,3 例患者出现创面裂开。其中 3 例患者在 1 个月左右的换药后愈合。另 1 例患者在 9 周后无改善,行二次手术,一期愈合。总之,COD 的继发感染是手术干预的指征,可能会阻止疾病进展。

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