Algera Joost, Lövdahl Jenny, Sjölund Jessica, Tornkvist Navkiran Thind, Törnblom Hans
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Expert Rev Gastroenterol Hepatol. 2023 Jul-Dec;17(9):871-881. doi: 10.1080/17474124.2023.2242775. Epub 2023 Aug 8.
Irritable bowel syndrome (IBS) is characterized by chronic symptoms (>6 months) of abdominal pain in combination with a disturbed bowel habit. There is an association between the intensity of abdominal pain and the need for health care utilization. A bidirectionally disordered gut-brain interaction is central in the pathophysiology of IBS where a number of factors, gastrointestinal and non-gastrointestinal, can contribute to the illness experience. In order to treat abdominal pain in IBS, mapping these factors in a multidimensional clinical profile is helpful.
This review covers basic epidemiology and pathophysiology of abdominal pain in IBS, the diagnostic approach, and a multidimensional treatment model where the management of abdominal pain is in focus.
A personalized treatment of abdominal pain in IBS is possible in patients who understand the diagnosis, the potential of therapies used, and where a good continuity in the patient-doctor relationship is established.
肠易激综合征(IBS)的特征是慢性(>6个月)腹痛症状,并伴有排便习惯紊乱。腹痛强度与医疗保健利用需求之间存在关联。双向紊乱的肠-脑相互作用是IBS病理生理学的核心,其中许多胃肠道和非胃肠道因素都可能导致疾病体验。为了治疗IBS中的腹痛,在多维临床概况中描绘这些因素是有帮助的。
本综述涵盖IBS中腹痛的基本流行病学和病理生理学、诊断方法以及以腹痛管理为重点的多维治疗模型。
对于理解诊断、所用治疗方法的潜力且建立了良好医患关系连续性的IBS患者,有可能进行个性化的腹痛治疗。