Kiremitler Nuri Burak, Kemerli Munteha Zeynep, Kayaci Nilgun, Karagoz Sultan, Pekdemir Sami, Sarp Gokhan, Sanduvac Senem, Onses Mustafa Serdar, Yilmaz Erkan
ERNAM-Erciyes University Nanotechnology Application and Research Center, 38039 Kayseri, Turkey.
Department of Materials Science and Engineering, Faculty of Engineering, Erciyes University, 38039 Kayseri, Turkey.
ACS Appl Nano Mater. 2022 Feb 28;5(5):6029-6054. doi: 10.1021/acsanm.2c00181. eCollection 2022 May 27.
Scientists, doctors, engineers, and even entire societies have become aware of the seriousness of the COVID-19 infection and are taking action quickly, using all the tools from protection to treatment against coronavirus SARS-CoV-2. Especially in this sense, scientific approaches and materials using nanotechnology are frequently preferred. In this review, we focus on how nanoscience and nanotechnology approaches can be used for protective equipment, diagnostic and treatment methods, medicine, and vaccine applications to stop the coronavirus SARS-CoV-2 and prevent its spread. SARS-CoV-2, which itself can be considered as a core-shell nanoparticle, can interact with various materials around it and remain bound for variable periods of time while maintaining its bioactivity. These applications are especially critical for the controlled use of disinfection systems. One of the most important processes in the fight against coronavirus is the rapid diagnosis of the virus in humans and the initiation of isolation and treatment processes. The development of nanotechnology-based test and diagnostic kits is another important research thrust. Nanotechnological therapeutics based on antiviral drug design and nanoarchitecture vaccines have been vital. Nanotechnology plays critical roles in the production of protective film surfaces for self-cleaning and antiviral masks, gloves, and laboratory clothes. An overview of literature studies highlighting nanotechnology and nanomaterial-based approaches to combat SARS-CoV-2 is presented.
科学家、医生、工程师乃至整个社会都已意识到新型冠状病毒肺炎（COVID-19）感染的严重性，并正在迅速采取行动，运用从防护到治疗冠状病毒SARS-CoV-2的所有手段。尤其在这方面，使用纳米技术的科学方法和材料经常受到青睐。在本综述中，我们重点关注纳米科学和纳米技术方法如何用于防护设备、诊断和治疗方法、药物以及疫苗应用，以阻止冠状病毒SARS-CoV-2并防止其传播。SARS-CoV-2本身可被视为一种核壳纳米颗粒，它能与周围的各种材料相互作用，并在保持其生物活性的同时，在不同时间段内保持结合状态。这些应用对于消毒系统的控制使用尤为关键。抗击冠状病毒最重要的过程之一是对人体中的病毒进行快速诊断，并启动隔离和治疗过程。基于纳米技术的检测和诊断试剂盒的开发是另一项重要的研究方向。基于抗病毒药物设计的纳米技术疗法和纳米结构疫苗至关重要。纳米技术在用于自清洁和抗病毒口罩、手套及实验室工作服的保护膜表面生产中发挥着关键作用。本文对突出纳米技术和基于纳米材料的抗击SARS-CoV-2方法的文献研究进行了综述。
