Roa Romero L, Gomez Cia T
Burns Incl Therm Inj. 1986 Jun;12(5):337-42. doi: 10.1016/0305-4179(86)90104-x.
An algorithm is presented for the qualitative and quantitative study of the variations in the distribution of the extracellular fluids and proteins between the vascular and interstitial spaces in burned patients using the values of the haematocrit, plasma protein concentration, fluid replacements and diuresis, measurements that are usually made in these type of patients. The observed fluid and protein shifts are indicative of the capillary dynamics of the burned patient and are in agreement with the known pathophysiology of the thermal injury. They provide a further means of studying the response of the patient to the treatment. The reliability of the algorithm has been assessed by comparing, retrospectively, the clinical progress with the results obtained in 39 patients, divided in four groups according to the burn surface area, as well as with experimental results gathered from the scientific/medical literature.
本文提出了一种算法，用于利用烧伤患者的血细胞比容、血浆蛋白浓度、补液量和尿量等通常在这类患者中进行的测量值，对烧伤患者血管和间质空间中细胞外液和蛋白质分布的变化进行定性和定量研究。观察到的液体和蛋白质转移表明了烧伤患者的毛细血管动力学，并且与已知的热损伤病理生理学相符。它们为研究患者对治疗的反应提供了进一步的手段。通过回顾性比较39例患者（根据烧伤表面积分为四组）的临床进展与所获结果，以及与从科学/医学文献中收集的实验结果，评估了该算法的可靠性。
