Salima Siti, Wibowo Mulyohadi Hadi, Dewayani Birgitta M, Nisa Aisyah Shofiatun, Alkaff Firas Farisi
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
Department of Pathology of Anatomy, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
Int J Womens Health. 2023 Aug 3;15:1239-1244. doi: 10.2147/IJWH.S421386. eCollection 2023.
Hydatidiform mole (HM) is an aberrant pregnancy characterized by atypical trophoblastic hyperplasia, hydropic chorionic villi, and deprived fetal development. There are two types of HM, ie, complete (CHM) and partial (PHM). Both CHM and PHM can recur; however, the recurrence of PHM is very scarce compared to CHM. In this report, we present a case of a 33-year-old woman with recurrent PHM for 7 times without any normal pregnancy in-between. PHM was determined by histology examination. The patient underwent suction curettage and was followed up with serial β-hCG levels. Recurrent PHM, although rare, is associated with an increased incidence of malignancy. A series of clinical and β-hCG evaluation should be warranted because of the possibility of gestational trophoblastic neoplasia development.
葡萄胎（HM）是一种异常妊娠，其特征为非典型滋养层细胞增生、绒毛水肿和胎儿发育缺失。HM有两种类型，即完全性葡萄胎（CHM）和部分性葡萄胎（PHM）。CHM和PHM均可复发；然而，与CHM相比，PHM的复发非常罕见。在本报告中，我们呈现了一例33岁女性反复发生7次PHM且其间无任何正常妊娠的病例。PHM通过组织学检查确诊。患者接受了刮宫术，并通过连续检测β - hCG水平进行随访。反复发生的PHM虽然罕见，但与恶性肿瘤发生率增加有关。鉴于存在发生妊娠滋养细胞肿瘤的可能性，应进行一系列临床和β - hCG评估。
