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关于使用Kono-S吻合术成功手术治疗一名克罗恩病患者的文献分析及病例研究

An Analysis of the Literature and a Case Study on the Successful Surgical Treatment of a Crohn's Patient Using a Kono-S Anastomosis.

作者信息

Saeed Mirza, Algahiny Ahmed Taymour, Elmitwalli Omar Samir Mohamed Megahed Saleh, Ahmed Mirit Mohamed Mohamed Refaat Mohamed, Juma Isam Mazin

机构信息

Department of General Surgery, King Hamad University Hospital, Muharraq, Bahrain.

School of Medicine, Royal College of Surgeons in Ireland - Medical University of Bahrain, Busaiteen, Muharraq, Bahrain.

出版信息

Euroasian J Hepatogastroenterol. 2023 Jan-Jun;13(1):36-39. doi: 10.5005/jp-journals-10018-1392.

DOI:10.5005/jp-journals-10018-1392
PMID:37554976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10405805/
Abstract

BACKGROUND

Crohn's disease (CD) is a chronic inflammatory bowel disease affecting the gastrointestinal tract. Treatment involves immunosuppression, and surgical intervention is sometimes necessary for patients who do not respond to medical treatment. However, recurrence of the disease is a common complication after surgery.

AIM

This case report focuses on a patient with CD who underwent ileocecal resection with Kono-S anastomosis, a surgical technique aimed at reducing recurrence rates.

CASE DESCRIPTION

A 43-year-old male with a known history of CD for 13 years presented with recurring moderate-to-severe lower abdominal pain associated with belching, nausea, subjective fever, and sweats. The patient was on infliximab and azathioprine. Investigations confirmed irregular skip mural thickening of ileal loops with significant luminal narrowing along with stenotic fibrostrictures of the ileum, and mild bilateral sacroiliitis. The patient was treated surgically with an ileocecal resection and a Kono-S anastomosis operation. This case report highlights the advantages and disadvantages of the Kono-S anastomosis technique in treating patients with recurrent CD.

CLINICAL SIGNIFICANCE

Kono-S anastomosis demonstrates a relative safety profile and carries several potential benefits. However, its wider adoption is limited due to insufficient familiarity among surgeons and the possibility of complications. Nevertheless, embracing Kono-S as the standard anastomosis method holds the promise of significant advantages for individuals with CD.

CONCLUSION

This case report highlights the potential benefits of Kono-S anastomosis in reducing CD recurrence and provides valuable insights for further research and clinical practice.

HOW TO CITE THIS ARTICLE

Saeed M, Algahiny AT, Elmitwalli OSMMS, . An Analysis of the Literature and a Case Study on the Successful Surgical Treatment of a Crohn's Patient Using a Kono-S Anastomosis. Euroasian J Hepato-Gastroenterol 2023;13(1):36-39.

摘要

背景

克罗恩病(CD)是一种影响胃肠道的慢性炎症性肠病。治疗包括免疫抑制,对于药物治疗无反应的患者有时需要手术干预。然而,疾病复发是手术后常见的并发症。

目的

本病例报告聚焦于一名接受回盲部切除并采用Kono-S吻合术的克罗恩病患者,该手术技术旨在降低复发率。

病例描述

一名有13年克罗恩病病史的43岁男性,出现反复的中重度下腹痛,伴有嗳气、恶心、主观发热和盗汗。该患者正在使用英夫利昔单抗和硫唑嘌呤。检查证实回肠袢不规则节段性壁增厚,伴有明显的管腔狭窄以及回肠狭窄性纤维狭窄,还有轻度双侧骶髂关节炎。该患者接受了回盲部切除和Kono-S吻合术。本病例报告强调了Kono-S吻合术在治疗复发性克罗恩病患者中的优缺点。

临床意义

Kono-S吻合术显示出相对安全的概况,并具有若干潜在益处。然而,由于外科医生对其不够熟悉以及可能出现并发症,其更广泛的应用受到限制。尽管如此,将Kono-S作为标准吻合方法有望为克罗恩病患者带来显著益处。

结论

本病例报告强调了Kono-S吻合术在降低克罗恩病复发方面的潜在益处,并为进一步研究和临床实践提供了有价值的见解。

如何引用本文

Saeed M, Algahiny AT, Elmitwalli OSMMS, 。关于使用Kono-S吻合术成功手术治疗一名克罗恩病患者的文献分析和病例研究。《欧亚肝脏胃肠病学杂志》2023;13(1):36 - 39。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/a5e869e17695/ejohg-13-36-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/3445b81f5ce8/ejohg-13-36-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/4f463228f9d1/ejohg-13-36-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/de0c9c0a7a25/ejohg-13-36-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/febd456088c5/ejohg-13-36-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/6654477af9c7/ejohg-13-36-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/db344387ca33/ejohg-13-36-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/0489d4747554/ejohg-13-36-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/a5e869e17695/ejohg-13-36-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/3445b81f5ce8/ejohg-13-36-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/4f463228f9d1/ejohg-13-36-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/de0c9c0a7a25/ejohg-13-36-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/febd456088c5/ejohg-13-36-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/6654477af9c7/ejohg-13-36-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/db344387ca33/ejohg-13-36-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/0489d4747554/ejohg-13-36-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f2/10405805/a5e869e17695/ejohg-13-36-g008.jpg

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Does anastomotic technique affects the recurrence rate of Crohn's disease after ileocolic resection?吻合技术会影响回结肠切除术后克罗恩病的复发率吗?
Ann Med Surg (Lond). 2021 Jan 19;62:164-167. doi: 10.1016/j.amsu.2021.01.027. eCollection 2021 Feb.
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Surgical Treatment for Crohn's Disease: A Role of Kono-S Anastomosis in the West.克罗恩病的外科治疗:小野-S吻合术在西方的作用。
Clin Colon Rectal Surg. 2020 Nov;33(6):335-343. doi: 10.1055/s-0040-1714236. Epub 2020 Sep 14.
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Experiences with the Kono-S anastomosis in Crohn's disease of the terminal ileum-a cohort study.克罗恩病末端回肠吻合术的经验-Kono-S 吻合术:一项队列研究。
Langenbecks Arch Surg. 2021 Jun;406(4):1173-1180. doi: 10.1007/s00423-020-01998-6. Epub 2020 Oct 6.
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Surgical Prevention of Anastomotic Recurrence by Excluding Mesentery in Crohn's Disease: The SuPREMe-CD Study - A Randomized Clinical Trial.手术排除克罗恩病肠系膜预防吻合口复发:SuPREMe-CD 研究——一项随机临床试验。
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