[Comparative evaluation of the cytogenetic effect of cyclophosphamide on lymphosarcoma cells and the bone marrow of intact and irradiated rats].

The paper deals with a comparative evaluation of cytogenetic action of cyclophosphamide on tumor and bone marrow cells in intact and radiation--exposed Pliss' lymphosarcoma-bearing mice. In both study groups, the level of cells with drug--induced chromosome damage was shown to be higher in tumor. No significant difference was established between the 2 groups in the effect of cyclophosphamide on similar tissues.