Bense Rico D, Steeghs Maurice H M, Eelkman Rooda Sebo Jan
Meander Medisch Centrum, afd. Interne Geneeskunde, Amersfoort.
Contact: Rico D. Bense (
Ned Tijdschr Geneeskd. 2023 Aug 2;167:D7367.
In recent years, there has been a growing advocacy to implement the use of balanced solutions like lactated Ringer's solution instead of normal saline as fluid therapy in non-critically ill patients. Currently, evidence shows that there might be a limited benefit of the use of Lactated Ringer's solution over saline in both in critically ill and non-critically ill patients. Lactated Ringer's solution is, in contrast to saline, incompatible with blood products and various frequently used intravenously administered drugs. The use of these drugs in conjunction with lactated Ringer's solution therefore requires additional precautionary measures. A hospital-wide transition from saline to lactated Ringer's solution might be beneficial for a subset of patients. However, a medication warning system is required for safe implementation.
近年来，越来越多的人主张在非危重症患者的液体治疗中使用平衡溶液，如乳酸林格氏液，而非生理盐水。目前，有证据表明，在危重症和非危重症患者中，使用乳酸林格氏液相对于生理盐水可能只有有限的益处。与生理盐水不同，乳酸林格氏液与血液制品和各种常用的静脉注射药物不相容。因此，将这些药物与乳酸林格氏液联合使用需要采取额外的预防措施。在全院范围内从生理盐水过渡到乳酸林格氏液可能对一部分患者有益。然而，安全实施需要一个用药警示系统。
