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美国创伤中心转运时间、距离和急诊科准备情况与儿科患者存活率的关系。

Association of Transport Time, Proximity, and Emergency Department Pediatric Readiness With Pediatric Survival at US Trauma Centers.

机构信息

Department of Surgery, Rutgers New Jersey Medical School, Newark.

Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health & Science University, Portland.

出版信息

JAMA Surg. 2023 Oct 1;158(10):1078-1087. doi: 10.1001/jamasurg.2023.3344.

DOI:10.1001/jamasurg.2023.3344
PMID:37556154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10413216/
Abstract

IMPORTANCE

Emergency department (ED) pediatric readiness is associated with improved survival among children. However, the association between geographic access to high-readiness EDs in US trauma centers and mortality is unclear.

OBJECTIVE

To evaluate the association between the proximity of injury location to receiving trauma centers, including the level of ED pediatric readiness, and mortality among injured children.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study used a standardized risk-adjustment model to evaluate the association between trauma center proximity, ED pediatric readiness, and in-hospital survival. There were 765 trauma centers (level I-V, adult and pediatric) that contributed data to the National Trauma Data Bank (January 1, 2012, through December 31, 2017) and completed the 2013 National Pediatric Readiness Assessment (conducted from January 1 through August 31, 2013). The study comprised children aged younger than 18 years who were transported by ground to the included trauma centers. Data analysis was performed between January 1 and March 31, 2022.

EXPOSURES

Trauma center proximity within 30 minutes by ground transport and ED pediatric readiness, as measured by weighted pediatric readiness score (wPRS; range, 0-100; quartiles 1 [low readiness] to 4 [high readiness]).

MAIN OUTCOMES AND MEASURES

In-hospital mortality. We used a patient-level mixed-effects logistic regression model to evaluate the association of transport time, proximity, and ED pediatric readiness on mortality.

RESULTS

This study included 212 689 injured children seen at 765 trauma centers. The median patient age was 10 (IQR, 4-15) years, 136 538 (64.2%) were male, and 127 885 (60.1%) were White. A total of 4156 children (2.0%) died during their hospital stay. The median wPRS at these hospitals was 79.1 (IQR, 62.9-92.7). A total of 105 871 children (49.8%) were transported to trauma centers with high-readiness EDs (wPRS quartile 4) and another 36 330 children (33.7%) were injured within 30 minutes of a quartile 4 ED. After adjustment for confounders, proximity, and transport time, high ED pediatric readiness was associated with lower mortality (highest-readiness vs lowest-readiness EDs by wPRS quartiles: adjusted odds ratio, 0.65 [95% CI, 0.47-0.89]). The survival benefit of high-readiness EDs persisted for transport times up to 45 minutes. The findings suggest that matching children to trauma centers with high-readiness EDs within 30 minutes of the injury location may have potentially saved 468 lives (95% CI, 460-476 lives), but increasing all trauma centers to high ED pediatric readiness may have potentially saved 1655 lives (95% CI, 1647-1664 lives).

CONCLUSIONS AND RELEVANCE

These findings suggest that trauma centers with high ED pediatric readiness had lower mortality after considering transport time and proximity. Improving ED pediatric readiness among all trauma centers, rather than selective transport to trauma centers with high ED readiness, had the largest association with pediatric survival. Thus, increased pediatric readiness at all US trauma centers may substantially improve patient outcomes after trauma.

摘要

重要性

急诊儿科准备情况与儿童生存率的提高有关。然而,在美国创伤中心,高准备度急诊儿科与死亡率之间的地理可达性关系尚不清楚。

目的

评估受伤地点与接收创伤中心的距离,包括急诊儿科准备程度,与受伤儿童死亡率之间的关系。

设计、设置和参与者:本回顾性队列研究使用标准化风险调整模型评估了创伤中心接近度、急诊儿科准备程度与院内生存率之间的关系。共有 765 家创伤中心(I-V 级,成人和儿科)向国家创伤数据库(2012 年 1 月 1 日至 2017 年 12 月 31 日)提供数据,并完成了 2013 年国家儿科准备度评估(2013 年 1 月 1 日至 8 月 31 日进行)。研究对象为年龄在 18 岁以下、通过地面运输到纳入创伤中心的儿童。数据分析于 2022 年 1 月 1 日至 3 月 31 日进行。

暴露因素

地面运输 30 分钟内的创伤中心接近度和急诊儿科准备程度,通过加权儿科准备评分(wPRS;范围 0-100;四分位数 1 [低准备度]至 4 [高准备度])来衡量。

主要结果和测量指标

院内死亡率。我们使用患者水平混合效应逻辑回归模型评估了运输时间、接近度和急诊儿科准备度对死亡率的关联。

结果

本研究纳入了 765 家创伤中心的 212689 名受伤儿童。患者的中位年龄为 10 岁(IQR,4-15 岁),136538 名(64.2%)为男性,127885 名(60.1%)为白人。共有 4156 名儿童(2.0%)在住院期间死亡。这些医院的中位 wPRS 为 79.1(IQR,62.9-92.7)。共有 105871 名儿童(49.8%)被送往准备程度高的急诊儿科的创伤中心(wPRS 四分位数 4),另有 36330 名儿童(33.7%)在四分位数 4 级 ED 附近受伤。在调整混杂因素、接近度和运输时间后,高 ED 儿科准备度与较低的死亡率相关(最高准备度与最低准备度 EDs 的 wPRS 四分位数:调整后的优势比,0.65[95%CI,0.47-0.89])。高准备度 ED 的生存获益在运输时间长达 45 分钟时仍然存在。研究结果表明,在受伤地点 30 分钟内将儿童与准备程度高的创伤中心相匹配,可能会挽救 468 条生命(95%CI,460-476 条生命),但将所有创伤中心提高到高 ED 儿科准备度,可能会挽救 1655 条生命(95%CI,1647-1664 条生命)。

结论和相关性

这些发现表明,考虑到运输时间和接近度后,准备程度高的急诊儿科创伤中心的死亡率较低。提高所有创伤中心的急诊儿科准备程度,而不是选择性地将患者转运至准备程度高的创伤中心,与儿科生存率的相关性最大。因此,增加美国所有创伤中心的儿科准备程度可能会显著改善创伤患者的预后。

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