Chen Jun-Yi, Wen Yi-Qun, Fang Long-Min, Chen Dong, Wang Jia-Liang, He Qing-Liu, Chen Guo-Feng
Department of Urology, The Second Hospital Affiliated to Fujian Medical University, Quanzhou, Fujian 362000, China.
Zhonghua Nan Ke Xue. 2022 Jul;28(7):603-607.
To investigate the correlation of the anterior lobe thickness of the prostate (ALTP) with bladder outlet obstruction (BOO), and evaluate the effect of ALTP on the clinical progression of BPH.
This retrospective study included 159 cases of BPH. We obtained the clinical indicators of the patients, including ALTP, prostate volume (PV), postvoid residual urine (PVR), maximum urinary flow rate (Qmax), BOO index (BOOI) and IPSS, and analyzed the correlations of ALTP with IPSS, PV, Qmax, age, PVR and BOOI. Using the ROC curve and cut-off point of ALTP, we compared the clinical indicators between the small and large ALTP groups, and analyzed the correlation between ALTP and the clinical progression of BPH.
IPSS was not significantly correlated with ALTP (P > 0.05), nor was ALTP with PV and Qmax (P > 0.05). The area under the ROC curve was 0.742 (95% CI: 0.656－0.828) and the cut-off point of ALTP was 0.65 cm. Statistically significant differences were observed in PV, Qmax, IPSS and the rate of surgery between the small ALTP (<0.65 cm) and large ALTP (≥0.65 cm) groups (P < 0.05).
ALTP is not proportional to PV or to IPSS. ALTP ≥ 0.65 cm increases the incidence of BOO, and may be a risk factor for the clinical progression of BPH.
探讨前列腺前叶厚度（ALTP）与膀胱出口梗阻（BOO）的相关性，并评估ALTP对良性前列腺增生（BPH）临床进展的影响。
这项回顾性研究纳入了159例BPH患者。我们获取了患者的临床指标，包括ALTP、前列腺体积（PV）、残余尿量（PVR）、最大尿流率（Qmax）、BOO指数（BOOI）和国际前列腺症状评分（IPSS），并分析了ALTP与IPSS、PV、Qmax、年龄、PVR和BOOI之间的相关性。利用ALTP的ROC曲线和切点，我们比较了ALTP小（<0.65 cm）、大（≥0.65 cm）两组之间的临床指标，并分析了ALTP与BPH临床进展之间的相关性。
IPSS与ALTP无显著相关性（P>0.05），ALTP与PV和Qmax也无显著相关性（P>0.05）。ROC曲线下面积为0.742（95%CI：0.656－0.828），ALTP的切点为0.65 cm。ALTP小（<0.65 cm）、大（≥0.65 cm）两组之间在PV、Qmax、IPSS和手术率方面存在统计学显著差异（P<0.05）。
ALTP与PV或IPSS不成正比。ALTP≥0.65 cm会增加BOO的发生率，可能是BPH临床进展的一个危险因素。
