Giesbrecht F G
Biometrics. 1986 Jun;42(2):437-48.
This paper presents an organized solution to the problem of computing inter- and intrablock analyses of incomplete block designs, based on the modified maximum likelihood principle proposed by Patterson and Thompson (1971, Biometrika 58, 545-554). The calculations are set out to be easily programmed on a microcomputer. The method is attractive because it is simple, yet sufficiently general to handle a wide class of designs, including partially balanced incomplete block designs, designs with unequal block sizes, designs with missing values, and generally unbalanced split-plot experiments.
本文基于帕特森和汤普森（1971年，《生物统计学》第58卷，第545 - 554页）提出的修正最大似然原理，针对不完全区组设计的区组间和区组内分析计算问题，给出了一种有条理的解决方案。这些计算过程便于在微型计算机上轻松编程。该方法具有吸引力，因为它简单，同时又足够通用，能够处理广泛的设计类型，包括部分平衡不完全区组设计、区组大小不等的设计、存在缺失值的设计，以及一般的不平衡裂区试验。
