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关于在银屑病中使用含有皮质类固醇的局部药物的共识声明。

Consensus Statements on the Use of Corticosteroid-Containing Topical Medications in Psoriasis.

出版信息

J Drugs Dermatol. 2023 Aug 1;22(8):736-741. doi: 10.36849/jdd.7453.

DOI:10.36849/jdd.7453
PMID:37556522
Abstract

This article aims to provide consensus statements on the use of corticosteroid-containing topical medications for the management of psoriasis. This Psoriasis Expert Group (PEG) includes dermatologist voting members with expertise in psoriasis who convened and evaluated the use of topical medications and previously published guidelines. A modified Delphi process was conducted to reach consensus results. Two rounds of voting were conducted for each topic and panel consensus was determined.  Nine statements were developed regarding topical medication efficacy, patient quality of life, frequency of application, medication "feel", and safety and tolerability. Dermatologist experts voted on the statements separately. Patients were not polled. All items received agreement: 15 with high consensus and 1 with moderate consensus.  For the treatment of psoriasis, the PEG agreed that patients and physicians prefer topical medications that are effective, provide long-lasting results, have a quick onset of action, and "feel good on the skin" with few adverse effects. The developed consensus statements provide guidance on the topical treatment of psoriasis, including combination therapies, such as a vitamin D and topical corticosteroid analog. These recommendations will be continuously reviewed and updated as more evidence continues to emerge.  April W. Armstrong AW, Reddy R, Khan S, et al. Consensus statements on the use of corticosteroid-containing topical medications in psoriasis. J Drugs Dermatol. 2023;22(8):736-741. doi:10.36849/JDD.7453.

摘要

这篇文章旨在就皮质类固醇类局部用药物治疗银屑病提供共识性声明。该银屑病专家组(PEG)由皮肤科投票成员组成,这些成员在银屑病方面具有专业知识,他们召集并评估了局部用药物和先前发表的指南的使用情况。采用改良 Delphi 法达成共识结果。针对每个主题进行了两轮投票,当专家组达成一致意见时,即确定为共识结果。共制定了 9 条关于局部用药物疗效、患者生活质量、应用频率、药物“感觉”以及安全性和耐受性的声明。皮肤科专家分别对这些声明进行了投票。未对患者进行民意调查。所有项目均达成一致意见:15 项为高度一致,1 项为中度一致。对于银屑病的治疗,PEG 专家组一致认为,患者和医生更喜欢疗效好、疗效持久、起效快且“皮肤感觉良好”、不良反应少的局部用药物。制定的共识性声明为银屑病的局部治疗提供了指导,包括维生素 D 和局部皮质类固醇类似物等联合治疗。随着更多证据的出现,这些建议将不断进行审查和更新。April W. Armstrong AW, Reddy R, Khan S, et al. Consensus statements on the use of corticosteroid-containing topical medications in psoriasis. J Drugs Dermatol. 2023;22(8):736-741. doi:10.36849/JDD.7453.

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