. Unidade de Terapia Intensiva, Hospital Alemão Oswaldo Cruz, São Paulo (SP) Brasil.
. Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo (SP) Brasil.
J Bras Pneumol. 2023 Aug 7;49(4):e20230046. doi: 10.36416/1806-3756/e20230046. eCollection 2023.
The world has been suffering from the COVID-19 pandemic. Some COVID-19 patients develop severe viral pneumonia, requiring mechanical ventilation and measures to treat refractory hypoxemia, such as a protective ventilation strategy, prone positioning, and the use of veno-venous extracorporeal membrane oxygenation (VV-ECMO). We describe a case series of 30 COVID-19 patients who needed VV-ECMO at the Hospital Alemão Oswaldo Cruz, located in the city of São Paulo, Brazil.
We included all patients who required VV-ECMO due to COVID-19 pneumonia between March of 2020 and June of 2021.
Prior to VV-ECMO, patients presented with the following median scores: SOFA score, 11; APPS score, 7; Respiratory ECMO Survival Prediction score, 2; and Murray score, 3.3. The 60-day-in-hospital mortality was 33.3% (n = 10).
Although our patients had a highly severe profile, our results were similar to those of other cohort studies in the literature. This demonstrates that VV-ECMO can be a good tool even in a pandemic situation when it is managed in an experienced center.
世界一直在遭受 COVID-19 大流行的影响。一些 COVID-19 患者发展为严重病毒性肺炎，需要机械通气和治疗难治性低氧血症的措施，如保护性通气策略、俯卧位和使用静脉-静脉体外膜肺氧合（VV-ECMO）。我们描述了巴西圣保罗市 Alemão Oswaldo Cruz 医院 30 例因 COVID-19 肺炎需要 VV-ECMO 的患者系列。
我们纳入了 2020 年 3 月至 2021 年 6 月期间因 COVID-19 肺炎需要 VV-ECMO 的所有患者。
在接受 VV-ECMO 之前，患者的中位数评分如下：SOFA 评分 11 分，APPS 评分 7 分，呼吸 ECMO 生存预测评分 2 分，Murray 评分 3.3 分。住院 60 天的死亡率为 33.3%（n=10）。
尽管我们的患者病情严重，但我们的结果与文献中的其他队列研究相似。这表明，即使在大流行情况下，在有经验的中心进行管理，VV-ECMO 也可以作为一种良好的工具。
