Universidade Federal do Paraná, Curitiba, PR, Brasil.
Pontifícia Universidade Católica do Paraná, Programa de Pós-Graduação em Ciências da Saúde, Ambulatório de Doenças Inflamatórias Intestinais, Curitiba, PR, Brasil.
Arq Gastroenterol. 2023 Apr-Jun;60(2):188-193. doi: 10.1590/S0004-2803.20230222-143.
•Diagnosis of microscopic colitis necessitates effective communication among gastroenterologists, endoscopists, and pathologists. •The gastroenterologist should refer every patient with chronic watery diarrhea to perform a colonoscopy in spite of the benign course of the disease and the absence of alarm symptoms. •The endoscopist should take 2 or 3 biopsy samples of the colonic mucosa from the right and left colon, put in separate recipients, despite that the mucosa looked macroscopically normal. •The pathologist should be encouraged to use objective histological criteria to make the diagnosis. Microscopic colitis is a chronic inflammatory bowel disease characterized by non-bloody diarrhea that can range from mild to severe. It is difficult to attribute up to 10-20% of chronic diarrhea to microscopic colitis. The three determinants factors of the diagnosis are characteristic clinical symptoms, normal endoscopic picture of the colon, and pathognomonic histological picture. This manuscript aimed to update considerations and recommendations for professionals involved (gastroenterologist, endoscopists and pathologist) in the diagnosis of MC. In addition, a short recommendation about treatment.
•显微镜结肠炎的诊断需要胃肠病学家、内镜医生和病理学家之间进行有效的沟通。
•尽管疾病呈良性经过且无报警症状，胃肠病学家仍应建议每一位慢性水样腹泻患者进行结肠镜检查。
•内镜医生应从右半结肠和左半结肠采集 2 或 3 块结肠黏膜活检标本，分别放入不同的容器中，尽管黏膜大体上看起来正常。
•应鼓励病理医生使用客观的组织学标准来做出诊断。显微镜结肠炎是一种慢性炎症性肠病，其特征为非血性腹泻，可从轻度到重度不等。高达 10-20%的慢性腹泻可归因于显微镜结肠炎。诊断的三个决定因素是特征性临床症状、结肠正常内镜表现和特征性组织学表现。本文旨在为参与 MC 诊断的专业人员（胃肠病学家、内镜医生和病理医生）提供最新的考虑因素和建议。此外，还对治疗提出了简短的建议。
