Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
Department of Cardiology, Iwate Prefectural Chubu Hospital.
Circ J. 2023 Sep 25;87(10):1347-1355. doi: 10.1253/circj.CJ-23-0188. Epub 2023 Aug 10.
It has been reported that patients with acute myocardial infarction (AMI) transferred to low-volume primary percutaneous coronary intervention (PCI) hospitals (<115/year) in low population density areas experience higher in-hospital mortality rates. This study compared in-hospital outcomes of patients admitted to high-volume primary PCI hospitals (≥115/year) with those for other regional general hospitals.
Retrospective analysis was conducted on data obtained from 2,453 patients with AMI admitted to hospitals in Iwate Prefecture (2014-2018). Multivariate analysis revealed that the in-hospital mortality rate of AMI among patients in regional general hospitals was significantly higher than among patients in high-volume hospitals. However, no significant difference in mortality rate was observed among patients with ST-elevation myocardial infarction (STEMI) undergoing primary PCI. Although no significant difference was found in the in-hospital mortality rate of patients with Killip class I STEMI, significantly lower in-hospital mortality rates were observed in patients admitted in high-volume hospitals for Killip classes II, III, and IV.
Although in-hospital outcomes for patients with STEMI undergoing primary PCI were similar, patients with heart failure or cardiogenic shock exhibited better in-hospital outcomes in high-volume primary PCI hospitals than those in regional general hospitals.
据报道,在人口密度较低的地区,转至低容量初级经皮冠状动脉介入治疗(PCI)医院(<115/年)的急性心肌梗死(AMI)患者的院内死亡率较高。本研究比较了高容量初级 PCI 医院(≥115/年)和其他地区综合医院收治的 AMI 患者的院内结局。
对 2014 年至 2018 年在岩手县医院就诊的 2453 例 AMI 患者的数据进行回顾性分析。多变量分析显示,区域综合医院 AMI 患者的院内死亡率明显高于高容量医院。然而,行直接 PCI 的 ST 段抬高型心肌梗死(STEMI)患者的死亡率无显著差异。虽然在直接 PCI 的 I 级 Killip 分类的 STEMI 患者中,院内死亡率无显著差异,但在 II、III 和 IV 级 Killip 分类的患者中,高容量医院的院内死亡率明显较低。
尽管直接 PCI 治疗 STEMI 患者的院内结局相似,但心力衰竭或心源性休克患者在高容量初级 PCI 医院的院内结局优于区域综合医院。