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比较行直接经皮冠状动脉介入治疗的高容量医院与区域综合医院的急性心肌梗死患者的住院结局。

Comparing In-Hospital Outcomes for Acute Myocardial Infarction Patients in High-Volume Hospitals Performing Primary Percutaneous Coronary Intervention vs. Regional General Hospitals.

机构信息

Division of Cardiology, Department of Internal Medicine, Iwate Medical University.

Department of Cardiology, Iwate Prefectural Chubu Hospital.

出版信息

Circ J. 2023 Sep 25;87(10):1347-1355. doi: 10.1253/circj.CJ-23-0188. Epub 2023 Aug 10.

Abstract

BACKGROUND

It has been reported that patients with acute myocardial infarction (AMI) transferred to low-volume primary percutaneous coronary intervention (PCI) hospitals (<115/year) in low population density areas experience higher in-hospital mortality rates. This study compared in-hospital outcomes of patients admitted to high-volume primary PCI hospitals (≥115/year) with those for other regional general hospitals.

METHODS AND RESULTS

Retrospective analysis was conducted on data obtained from 2,453 patients with AMI admitted to hospitals in Iwate Prefecture (2014-2018). Multivariate analysis revealed that the in-hospital mortality rate of AMI among patients in regional general hospitals was significantly higher than among patients in high-volume hospitals. However, no significant difference in mortality rate was observed among patients with ST-elevation myocardial infarction (STEMI) undergoing primary PCI. Although no significant difference was found in the in-hospital mortality rate of patients with Killip class I STEMI, significantly lower in-hospital mortality rates were observed in patients admitted in high-volume hospitals for Killip classes II, III, and IV.

CONCLUSIONS

Although in-hospital outcomes for patients with STEMI undergoing primary PCI were similar, patients with heart failure or cardiogenic shock exhibited better in-hospital outcomes in high-volume primary PCI hospitals than those in regional general hospitals.

摘要

背景

据报道,在人口密度较低的地区,转至低容量初级经皮冠状动脉介入治疗(PCI)医院(<115/年)的急性心肌梗死(AMI)患者的院内死亡率较高。本研究比较了高容量初级 PCI 医院(≥115/年)和其他地区综合医院收治的 AMI 患者的院内结局。

方法和结果

对 2014 年至 2018 年在岩手县医院就诊的 2453 例 AMI 患者的数据进行回顾性分析。多变量分析显示,区域综合医院 AMI 患者的院内死亡率明显高于高容量医院。然而,行直接 PCI 的 ST 段抬高型心肌梗死(STEMI)患者的死亡率无显著差异。虽然在直接 PCI 的 I 级 Killip 分类的 STEMI 患者中,院内死亡率无显著差异,但在 II、III 和 IV 级 Killip 分类的患者中,高容量医院的院内死亡率明显较低。

结论

尽管直接 PCI 治疗 STEMI 患者的院内结局相似,但心力衰竭或心源性休克患者在高容量初级 PCI 医院的院内结局优于区域综合医院。

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