Lorthe Elsa, Richard Viviane, Dumont Roxane, Loizeau Andrea, Perez-Saez Javier, Baysson Hélène, Zaballa Maria-Eugenia, Lamour Julien, Pullen Nick, Schrempft Stephanie, Barbe Rémy P, Posfay-Barbe Klara M, Guessous Idris, Stringhini Silvia
Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and Statistics Paris (CRESS), Paris, France.
SSM Popul Health. 2023 Jul 23;23:101472. doi: 10.1016/j.ssmph.2023.101472. eCollection 2023 Sep.
Children and adolescents are highly vulnerable to the impact of sustained stressors during developmentally sensitive times. We investigated how demographic characteristics intersect with socioeconomic dimensions to shape the social patterning of quality of life and mental health in children and adolescents, two years into the COVID-19 pandemic.
We used data from the prospective SEROCoV-KIDS cohort study of children and adolescents living in Geneva (Switzerland, 2022). We conducted an intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy by nesting participants within 48 social strata defined by intersecting sex, age, immigrant background, parental education and financial hardship in Bayesian multilevel logistic models for poor health-related quality of life (HRQoL, measured with PedsQL) and mental health difficulties (measured with the Strengths and Difficulties Questionnaire).
Among participants aged 2-17 years, 240/2096 (11.5%, 95%CI 10.1-12.9) had poor HRQoL and 105/2135 (4.9%, 95%CI 4.0-5.9) had mental health difficulties. The predicted proportion of poor HRQoL ranged from 3.4% for 6-11 years old Swiss girls with highly educated parents and no financial hardship to 34.6% for 12-17 years old non-Swiss girls with highly educated parents and financial hardship. Intersectional strata involving adolescents and financial hardship showed substantially worse HRQoL than their counterparts. Between-stratum variations in the predicted frequency of mental health difficulties were limited (range 4.4%-6.5%).
We found considerable differences in adverse outcomes across social strata. Our results suggest that, post-pandemic, interventions to address social inequities in HRQoL should focus on specific intersectional strata involving adolescents and families experiencing financial hardship, while those aiming to improve mental health should target all children and adolescents.
儿童和青少年在发育敏感时期极易受到持续压力源的影响。我们调查了在新冠疫情爆发两年后,人口统计学特征如何与社会经济维度相互作用,从而塑造儿童和青少年生活质量及心理健康的社会模式。
我们使用了来自瑞士日内瓦儿童和青少年前瞻性SEROCoV-KIDS队列研究的数据。我们通过将参与者嵌套在由性别、年龄、移民背景、父母教育程度和经济困难交叉定义的48个社会阶层中,在贝叶斯多水平逻辑模型中对个体异质性和歧视准确性进行交叉多水平分析,以评估健康相关生活质量差(HRQoL,用儿童生活质量量表PedsQL测量)和心理健康问题(用优势与困难问卷测量)。
在2至17岁的参与者中,240/2096(11.5%,95%CI 10.1-12.9)的HRQoL较差,105/2135(4.9%,95%CI 4.0-5.9)有心理健康问题。HRQoL差的预测比例从父母受过高等教育且无经济困难的6至11岁瑞士女孩的3.4%到父母受过高等教育且有经济困难的12至17岁非瑞士女孩的34.6%不等。涉及青少年和经济困难的交叉阶层的HRQoL明显比其他阶层差。心理健康问题预测频率的阶层间差异有限(范围为4.4%-6.5%)。
我们发现不同社会阶层的不良后果存在显著差异。我们的结果表明,疫情后,解决HRQoL方面社会不平等问题的干预措施应侧重于涉及青少年和经历经济困难家庭的特定交叉阶层,而旨在改善心理健康的措施应针对所有儿童和青少年。