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Front Oncol. 2023 Jul 25;13:1257622. doi: 10.3389/fonc.2023.1257622. eCollection 2023.
2
Corrigendum: Editorial: Targeting DNA damage response to enhance antitumor innate immunity in radiotherapy.勘误：社论：靶向DNA损伤反应以增强放疗中的抗肿瘤固有免疫
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J Immunother Cancer. 2022 Oct;10(10). doi: 10.1136/jitc-2022-005020.
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Tumor microenvironment-responsive manganese-based nano-modulator activate the cGAS-STING pathway to enhance innate immune system response.肿瘤微环境响应性锰基纳米调节剂激活 cGAS-STING 通路增强固有免疫系统反应。
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本文引用的文献

1
Inhibition of the CD47-SIRPα axis for cancer therapy: A systematic review and meta-analysis of emerging clinical data.抑制 CD47-SIRPα 轴用于癌症治疗：新兴临床数据的系统评价和荟萃分析。
Front Immunol. 2022 Nov 11;13:1027235. doi: 10.3389/fimmu.2022.1027235. eCollection 2022.
2
ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer.ATR 介导的 CD47 和 PD-L1 上调限制结直肠癌放疗诱导的免疫原性和远隔效应。
Sci Immunol. 2022 Jun 10;7(72):eabl9330. doi: 10.1126/sciimmunol.abl9330.
3
DNA-PK Inhibition and Radiation Promote Antitumoral Immunity through RNA Polymerase III in Pancreatic Cancer.DNA-PK 抑制和放疗通过 RNA 聚合酶 III 促进胰腺癌中的抗肿瘤免疫。
Mol Cancer Res. 2022 Jul 6;20(7):1137-1150. doi: 10.1158/1541-7786.MCR-21-0725.
4
Immunomodulation by radiotherapy in tumour control and normal tissue toxicity.放射治疗在肿瘤控制和正常组织毒性中的免疫调节作用。
Nat Rev Immunol. 2022 Feb;22(2):124-138. doi: 10.1038/s41577-021-00568-1. Epub 2021 Jul 1.
5
Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance.线粒体 DNA 断裂的核感应增强免疫监视。
Nature. 2021 Mar;591(7850):477-481. doi: 10.1038/s41586-021-03269-w. Epub 2021 Feb 24.
6
Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer.奥拉帕利联合放疗和 ATR 抑制剂的组合疗效需要同源重组修复有效的胰腺癌细胞中的 PARP1 蛋白。
Mol Cancer Ther. 2021 Feb;20(2):263-273. doi: 10.1158/1535-7163.MCT-20-0365. Epub 2020 Dec 2.
7
Radiation Therapy and the In Situ Vaccination Approach.放射治疗与原位疫苗接种方法。
Int J Radiat Oncol Biol Phys. 2020 Nov 15;108(4):891-898. doi: 10.1016/j.ijrobp.2020.08.023. Epub 2020 Aug 12.
8
Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy.线粒体 DNA 驱动放疗的远隔效应，自噬会抑制这种远隔效应。
Nat Immunol. 2020 Oct;21(10):1160-1171. doi: 10.1038/s41590-020-0751-0. Epub 2020 Aug 3.
9
ATR inhibition potentiates ionizing radiation-induced interferon response via cytosolic nucleic acid-sensing pathways.ATR 抑制通过细胞质核酸感应途径增强电离辐射诱导的干扰素反应。
EMBO J. 2020 Jul 15;39(14):e104036. doi: 10.15252/embj.2019104036. Epub 2020 Jun 2.
10
Priming and Propagating Anti-tumor Immunity: Focal Hypofractionated Radiation for in Situ Vaccination and Systemic Targeted Radionuclide Theranostics for Immunomodulation of Tumor Microenvironments.引发和传播抗肿瘤免疫：适形低分割放射用于原位疫苗接种和系统靶向放射性核素治疗学以调节肿瘤微环境的免疫。
Semin Radiat Oncol. 2020 Apr;30(2):181-186. doi: 10.1016/j.semradonc.2019.12.008.

Editorial: Targeting DNA damage response to enhance antitumor innate immunity in radiotherapy.

作者信息

Valvo Victoria M, Vitale Emanuele, Tigano Marco, Evans Rachel, Morgan Meredith A, Zhang Qiang

机构信息

Department of Radiation Oncology, Rogel Cancer Center, University of Michigan, Ann Arbor, MI, United States.

Cancer Biology Program, University of Michigan, Ann Arbor, MI, United States.

出版信息

Front Oncol. 2023 Jul 25;13:1257622. doi: 10.3389/fonc.2023.1257622. eCollection 2023.

DOI:10.3389/fonc.2023.1257622
PMID:37560464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10408123/
Abstract
摘要