Haneke E
Z Hautkr. 1979 May 1;54(9):408-14.
More than 180 patients were treated for immunostimulation with levamisole within three and a half years. The results were statistically evaluated in 128 subjects. A highly significant improvement was noted in 44 patients suffering from recurrent herpes simplex labialis, facialis and oralis. 14 patients with recurrent herpes genitalis, lumbalis and glutaealis only experienced a reduction of the recurrence frequency. Aphthae in 16 subjects became less frequent and pain was reduced. Levamisole should be tried in recalcitrant chronic candidoses and bacterial infections not responding to specific antibiotic treatment. Slight side effects are relatively frequent, but severe ones are only rarely observed.
在三年半的时间里,超过180名患者接受了左旋咪唑免疫刺激治疗。对128名受试者的结果进行了统计学评估。44例复发性唇、面部和口腔单纯疱疹患者有显著改善。14例复发性生殖器、腰部和臀部疱疹患者仅复发频率有所降低。16例患者的口疮发作频率降低且疼痛减轻。对于顽固性慢性念珠菌病和对特定抗生素治疗无反应的细菌感染,应尝试使用左旋咪唑。轻微副作用相对常见,但严重副作用很少见。