Van de Heyning J
Laryngoscope. 1978 Mar;88(3):522-7. doi: 10.1288/00005537-197803000-00015.
In a pilot study as well as in a double-blind placebo-controlled study, 21 patients suffering from recurrent aphthous stomatitis were treated with the immunotherapeutic agent, levamisole. The results obtained confirm previous studies that levamisole has a beneficial effect on the symptoms of recurrent aphthous stomatitis and is well-tolerated.