Queen Mary University of London, School of Medicine and Dentistry.
Royal London Hospital, Barts Health NHS Trust, London, UK.
Curr Opin Obstet Gynecol. 2023 Oct 1;35(5):453-459. doi: 10.1097/GCO.0000000000000901. Epub 2023 Aug 9.
To explore the recent literature concerning the effect of gestational diabetes (GDM) on adverse pregnancy outcomes (APO).
Literature search on PubMed, Medline and British Journal of Obstetrics and Gynaecology was conducted using keywords. Search fields were filtered down to include articles from 2019 onwards. GDM is common during pregnancy and is on the rise because of increasing in obesity rates. GDM tended to show an increased risk of APO compared with non-GDM. Treatment of these pregnancies tended to improve these outcomes, particularly for LGA and macrosomia. Additional factors such as prepregnancy BMI and gestational weight gain (GWG) were shown to influence risk. More studies are needed to determine the true effect on postpartum haemorrhage (PPH) and induction of labour (IOL).
The review agrees with the findings from previous studies and adds to the current literature. Early intervention to manage glycaemic control and GWG may help improve these outcomes. Public health strategies that tackle obesity rates will help to reduce prepregnancy BMI and, therefore, rates of GDM.
探讨妊娠糖尿病（GDM）对不良妊娠结局（APO）的影响的最新文献。
使用关键词在 PubMed、Medline 和英国妇产科杂志上进行文献检索。搜索字段被过滤到包括 2019 年以后的文章。由于肥胖率的增加，妊娠期间 GDM 很常见，且呈上升趋势。与非 GDM 相比，GDM 往往显示出更高的 APO 风险。这些妊娠的治疗往往可以改善这些结局，特别是对于巨大儿和巨婴。其他因素，如孕前 BMI 和孕期体重增加（GWG），也显示出对风险的影响。需要更多的研究来确定对产后出血（PPH）和引产（IOL）的真正影响。
综述与之前的研究结果一致，并补充了当前的文献。早期干预以控制血糖和 GWG 可能有助于改善这些结局。解决肥胖率的公共卫生策略将有助于降低孕前 BMI，从而降低 GDM 的发生率。
