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评价部分性脾动脉栓塞术后脾脏梗死率和血小板增高率。

Evaluation of splenic infarction ratio and platelet increase ratio after partial splenic artery embolization.

机构信息

Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, 1-5-1, Sendagi, Bunkyo-ku, Tokyo, Japan.

Department of Gastrointestinal Surgery, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi, Nakahara-ku, Kawasaki city, Kanagawa, Japan.

出版信息

J Int Med Res. 2023 Aug;51(8):3000605231190967. doi: 10.1177/03000605231190967.

DOI:10.1177/03000605231190967
PMID:37560966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10416656/
Abstract

OBJECTIVE

The spleen is part of the lymphatic system and is one of the least understood organs of the human body. It is involved in the production of blood cells and helps filter the blood, remove old blood cells, and fight infection. Partial splenic artery embolization (PSE) is widely used to treat pancytopenia and portal hypertension. The efficacy of PSE for improving thrombocytopenia has been well demonstrated. In this study, we evaluated the splenic infarction ratio and platelet increase ratio after PSE.

METHODS

Forty-five consecutive patients underwent PSE from January 2014 to August 2022. We retrospectively evaluated the splenic infarction volume and ratio after PSE and analyzed the relationship between the splenic infarction ratio and platelet increase ratio after PSE.

RESULTS

The platelet increase ratio was correlated with the splenic infarction ratio after PSE. The cutoff value for the splenic infarction ratio with a two-fold platelet increase was 63.0%.

CONCLUSION

We suggest performance of PSE in patients with a splenic infarction ratio of 63% to double the expected platelet count.

摘要

目的

脾脏是淋巴系统的一部分，也是人体最不被了解的器官之一。它参与血细胞的生成，并有助于过滤血液、清除老化的血细胞和抵御感染。部分性脾动脉栓塞术（PSE）广泛用于治疗全血细胞减少症和门静脉高压症。PSE 改善血小板减少症的疗效已得到充分证实。在本研究中，我们评估了 PSE 后脾梗死的比例和血小板增加的比例。

方法

2014 年 1 月至 2022 年 8 月，连续 45 例患者接受 PSE。我们回顾性评估了 PSE 后的脾梗死体积和比例，并分析了 PSE 后脾梗死比例与血小板增加比例之间的关系。

结果

血小板增加比例与 PSE 后的脾梗死比例相关。血小板增加两倍时脾梗死比例的临界值为 63.0%。

结论

我们建议在脾梗死比例为 63%时行 PSE，以达到预期血小板计数增加两倍的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/aa385b936351/10.1177_03000605231190967-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/5b54510d9cc9/10.1177_03000605231190967-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/eda9b281c79f/10.1177_03000605231190967-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/aa385b936351/10.1177_03000605231190967-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/5b54510d9cc9/10.1177_03000605231190967-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/eda9b281c79f/10.1177_03000605231190967-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097b/10416656/aa385b936351/10.1177_03000605231190967-fig3.jpg

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本文引用的文献

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2
Repeated partial splenic artery embolization for hypersplenism improves platelet count.重复部分脾动脉栓塞术治疗脾功能亢进可提高血小板计数。
Open Med (Wars). 2022 Apr 25;17(1):808-815. doi: 10.1515/med-2022-0479. eCollection 2022.
3
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单纯性肝囊肿的处理。
J Nippon Med Sch. 2022 Mar 11;89(1):2-8. doi: 10.1272/jnms.JNMS.2022_89-115. Epub 2021 Sep 14.
4
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J Gastroenterol. 2021 Apr;56(4):382-394. doi: 10.1007/s00535-021-01762-7. Epub 2021 Feb 24.
5
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6
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7
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8
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9
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