Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School.
J Nippon Med Sch. 2022 Mar 11;89(1):2-8. doi: 10.1272/jnms.JNMS.2022_89-115. Epub 2021 Sep 14.
Simple hepatic cysts are typically saccular, thin-walled masses with fluid-filled epithelial lined cavities. They arise from aberrant bile duct cells that develop during embryonic development. With the development of diagnostic modalities such as ultrasonography (US), CT, and MRI, simple hepatic cysts are frequently detected in clinical examinations. US is the most useful and noninvasive tool for diagnosis of simple hepatic cysts and can usually differentiate simple hepatic cysts from abscesses, hemangiomas, and malignancies. Cysts with irregular walls, septations, calcifications, or daughter cysts on US should be evaluated with enhanced CT or MRI, to differentiate simple hepatic cysts from cystic neoplasms or hydatid cysts. Growth and compression of hepatic cysts cause abdominal discomfort, pain, distension, and dietary symptoms such as nausea, vomiting, a feeling of fullness, and early satiety. Complications of simple hepatic cysts include infection, spontaneous hemorrhage, rupture, and external compression of biliary tree or major vessels. Asymptomatic simple hepatic cysts do not require treatment. Treatment for symptomatic simple hepatic cysts includes percutaneous aspiration, aspiration followed by sclerotherapy, and surgery. The American College of Gastroenterology clinical guidelines recommend laparoscopic fenestration because of its high success rate and low invasiveness. Percutaneous procedures for treatment of simple hepatic cysts are particularly effective for immediate palliation of patient symptoms; however, they are not generally recommended because of the high rate of recurrence. Management of simple hepatic cysts requires correct differentiation from neoplasms and infections, and selection of a reliable treatment.
单纯性肝囊肿通常为薄壁、囊状、充满液体的上皮衬里腔隙。它们是由胚胎发育过程中异常的胆管细胞发展而来。随着超声(US)、CT 和 MRI 等诊断方式的发展,单纯性肝囊肿在临床检查中经常被发现。US 是诊断单纯性肝囊肿最有用和非侵入性的工具,通常可以将单纯性肝囊肿与脓肿、血管瘤和恶性肿瘤区分开来。US 上显示囊肿壁不规则、分隔、钙化或子囊的囊肿应通过增强 CT 或 MRI 进行评估,以将单纯性肝囊肿与囊性肿瘤或包虫囊肿区分开来。肝囊肿的生长和压迫会引起腹部不适、疼痛、腹胀以及恶心、呕吐、饱腹感和早饱等饮食症状。单纯性肝囊肿的并发症包括感染、自发性出血、破裂以及胆道或大血管受压。无症状的单纯性肝囊肿不需要治疗。有症状的单纯性肝囊肿的治疗包括经皮抽吸、抽吸后硬化治疗和手术。美国胃肠病学院的临床指南建议腹腔镜开窗术,因为其成功率高且侵袭性低。经皮治疗单纯性肝囊肿的方法特别有效,可以立即缓解患者的症状;然而,由于复发率高,一般不推荐使用这些方法。单纯性肝囊肿的管理需要正确地区分肿瘤和感染,并选择可靠的治疗方法。