Universidade Estadual Paulista (Unesp), Faculdade de Medicina de Botucatu, Departamento de Anestesiologia, Botucatu, SP, Brazil.
Universidade Estadual Paulista (Unesp), Faculdade de Medicina de Botucatu, Departamento de Anestesiologia, Botucatu, SP, Brazil.
Braz J Anesthesiol. 2024 Jul-Aug;74(4):744457. doi: 10.1016/j.bjane.2023.08.001. Epub 2023 Aug 9.
There are few studies related to Coronavirus Disease 2019 (COVID-19) on the prevalence and nature of pain symptoms after hospital discharge, especially in individuals who develop moderate to severe disease forms. Therefore, this study aimed to evaluate the presence of chronic pain in patients discharged after hospitalization for COVID-19, and the relationship between the presence of chronic pain and intensive care stay, demographics, and risk factors for the worst Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outcome.
A cross-sectional observational study was carried out on patients with COVID-19 who recovered after hospitalization. Patients were recruited at the least 3 months after discharge and their hospital's health files were prospected. The variables evaluated were demographics, the severity of SARS-CoV-2 infection (considering the need for intensive care), and the presence of chronic pain. The results were shown in a descriptive manner, and multivariate analysis expressed as Odds Ratios (ORs) and respective Confidence Intervals (CIs) for the outcomes studied. Statistical significance was set at p < 0.05.
Of 242 individuals included, 77 (31.8%) reported chronic pain related to COVID-19, with no correlation with the severity of infection. Female sex and obesity were associated with a higher risk for chronic pain with ORs of 2.69 (Confidence Interval [95% CI 1.4 to 5.0]) and 3.02 (95% CI 1.5 to 5.9). The limbs were the most affected areas of the body.
Chronic pain is common among COVID-19 survivors treated in hospital environments. Female sex and obesity are risk factors for its occurrence.
关于新冠肺炎（COVID-19）患者出院后疼痛症状的发生率和性质，尤其是在发展为中重度疾病的个体中，相关研究较少。因此，本研究旨在评估 COVID-19 住院患者出院后慢性疼痛的发生情况，以及慢性疼痛与重症监护病房入住时间、人口统计学特征和严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）不良结局的危险因素之间的关系。
对已住院康复的 COVID-19 患者进行横断面观察性研究。患者在出院后至少 3 个月时招募，并查阅其医院的健康档案。评估的变量包括人口统计学特征、SARS-CoV-2 感染的严重程度（考虑是否需要重症监护）以及慢性疼痛的发生情况。结果以描述性方式呈现，并通过多变量分析以比值比（OR）及其置信区间（95%CI）表示研究结果的相关性。以 p < 0.05 为统计学显著性标准。
在 242 名纳入的患者中，77 名（31.8%）报告与 COVID-19 相关的慢性疼痛，与感染严重程度无相关性。女性和肥胖与慢性疼痛的发生风险增加相关，OR 值分别为 2.69（95%CI 1.4 至 5.0）和 3.02（95%CI 1.5 至 5.9）。四肢是受影响最严重的身体部位。
在住院环境中治疗的 COVID-19 幸存者中，慢性疼痛很常见。女性和肥胖是其发生的危险因素。
