Huo Yu-Jia, Zhao Wei-Li
Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; Pôle de Recherches Sino-Français en Science du Vivant et Génomique, Laboratory of Molecular Pathology, Shanghai, China.
Semin Hematol. 2023 Jul;60(3):173-177. doi: 10.1053/j.seminhematol.2023.07.003. Epub 2023 Jul 26.
Natural killer (NK)/T-cell lymphomas (NK/TCL) and peripheral T-cell lymphomas (PTCL) are aggressive hematological malignancies. With the development of next-generation sequencing, circulating tumor DNA (ctDNA) can be detected by several techniques with clinical implications. So far, the effect of ctDNA in pretreatment prognosis prediction, longitudinal monitoring of treatment response and surveillance of long-term remission or relapse in NK/TCL and PTCL has been reported in several researches.
自然杀伤（NK）/T细胞淋巴瘤（NK/TCL）和外周T细胞淋巴瘤（PTCL）是侵袭性血液系统恶性肿瘤。随着下一代测序技术的发展，循环肿瘤DNA（ctDNA）可通过多种具有临床意义的技术检测到。到目前为止，多项研究已经报道了ctDNA在NK/TCL和PTCL的预处理预后预测、治疗反应的纵向监测以及长期缓解或复发监测中的作用。
