[急性冠状动脉闭塞期间苹果酸和烟酰胺腺嘌呤二核苷酸对局部心肌收缩的影响]
[Effect of malate and NAD on local myocardial contraction during acute coronary occlusion].
作者信息
Kostin V I
出版信息
Biull Eksp Biol Med. 1986 Sep;102(9):303-5.
PMID:3756330
Abstract
In acute experiments on cats the effects of malate (100 mg/kg), NAD (0.2 mg/kg) and their combination on regional myocardial contractility were studied during acute coronary artery occlusion. All the drugs increased significantly myocardial contractility in border and intact zones. However, the response of the central ischemic zone to drug effects was insignificant.
摘要
在对猫进行的急性实验中，研究了苹果酸盐（100毫克/千克）、烟酰胺腺嘌呤二核苷酸（NAD，0.2毫克/千克）及其组合在急性冠状动脉闭塞期间对局部心肌收缩性的影响。所有药物均显著增强了边缘区和正常区的心肌收缩性。然而，中央缺血区对药物作用的反应不明显。
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