Alqahtani Hussam M, Koroukian Siran M, Stange Kurt C, Schiltz Nicholas K, Bissada Nabil F
Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Department of Preventive Dental Science, College of Dentistry, King Saud Bin Abdelaziz University for Health Sciences, Riyadh, Saudi Arabia.
J Int Soc Prev Community Dent. 2023 Jun 29;13(3):247-257. doi: 10.4103/jispcd.JISPCD_11_23. eCollection 2023 May-Jun.
The aim of this study was to evaluate whether periodontal disease (PD) moderates the association between complex multimorbidity (MM) and fair/poor general health in a US representative sample of older individuals.
This study identified 937 participants who were at least 60 years of age from the 2013-2014 National Health and Nutrition Examination Survey. A multivariable logistic regression model was used to estimate the association between complex MM (including chronic conditions, functional limitations, and geriatric syndromes) and self-reported fair/poor general health. Subsequently, we specified interactions between complex MM and PD to determine whether PD moderates the effect of complex MM on fair/poor general health.
Nineteen percent of participants reported fair/poor general health. Complex MM was associated with 2.2 times greater odds of self-reported fair/poor health. However, PD was neither independently associated with fair/poor health nor an effect modifier for the association between complex MM and fair/poor general health. Age, white race, those with at least a high-school education level, a family income-to-poverty ratio of at least 2, former smoking status, and being married were significantly associated with fair/poor general health.
Complex MM, but not PD, was associated with greater odds to report fair/poor general health, and PD did not moderate the association between complex MM and fair/poor general health. People with complex MM are more likely to have worse general health; however, PD did not strengthen this association. Further studies are needed to evaluate whether treatment for PD for people vulnerable to the development of complex MM has a positive effect on their general health.
本研究旨在评估在美国具有代表性的老年人群样本中，牙周疾病（PD）是否会缓和复杂多重疾病（MM）与一般健康状况为“一般/较差”之间的关联。
本研究从2013 - 2014年国家健康与营养检查调查中确定了937名年龄至少为60岁的参与者。使用多变量逻辑回归模型来估计复杂MM（包括慢性病、功能受限和老年综合征）与自我报告的一般健康状况为“一般/较差”之间的关联。随后，我们设定了复杂MM与PD之间的相互作用，以确定PD是否会缓和复杂MM对一般健康状况为“一般/较差”的影响。
19%的参与者报告其一般健康状况为“一般/较差”。复杂MM与自我报告的健康状况为“一般/较差”的几率高2.2倍相关。然而，PD既不与健康状况为“一般/较差”独立相关，也不是复杂MM与一般健康状况为“一般/较差”之间关联的效应修饰因素。年龄、白人种族、至少具有高中教育水平、家庭收入与贫困比率至少为2、曾经吸烟状况以及已婚与一般健康状况为“一般/较差”显著相关。
复杂MM而非PD与报告一般健康状况为“一般/较差”的几率更高相关，且PD并未缓和复杂MM与一般健康状况为“一般/较差”之间的关联。患有复杂MM的人更有可能总体健康状况较差；然而，PD并未强化这种关联。需要进一步研究来评估对易患复杂MM的人群进行PD治疗是否对其总体健康有积极影响。
