Ibrahim Dayang Fadzlina Abang, Venkiteswaran Annapurny, Hasmun Noren Nor
Centre of Paediatric Dentistry and Orthodontics Studies, Faculty of Dentistry, Universiti Teknologi MARA, Selangor, Malaysia.
Department of Oral Science, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
J Int Soc Prev Community Dent. 2023 Jun 29;13(3):194-207. doi: 10.4103/jispcd.JISPCD_36_23. eCollection 2023 May-Jun.
Studies on resin infiltration and its penetration capability are becoming the focus of emerging dentistry. The depth of resin penetration could be a key determining factor in creating a diffusion barrier and in the success of infiltration. The aim of this review article was to evaluate the penetration depth of commercially available resin infiltration in early caries lesions and to identify factors that influence the penetration capability of resin infiltration.
A literature search was performed in four databases (PubMed, Science Direct, Scopus, and Web of Science) and manual searching from 2009 to December 2022. Eligibility criteria included studies pertaining to factors affecting the penetration depth of resin infiltration into the enamel. The risk of bias assessment was done by using checklist for reporting studies (CRIS).
The initial search resulted in a total of 297 studies. Twenty-nine were assessed for eligibility, and 23 were selected in the qualitative synthesis. According to the CRIS guidelines, all of the studies were classified as moderate risk of bias. The penetration of resin infiltration is influenced by the enamel surface treatment with hydrochloric acid, formulations containing triethylene glycol dimethacrylate (TEGDMA), the addition of ethanol, penetration time, duration of penetration time, saliva contamination, caries activity, and type of tooth. The hypermineralized surface layer needs to be removed for better resin perfusion.
The key to optimal resin infiltration depends on the enamel surface treatment with hydrochloric acid and application technique, infiltration duration, formulation of TEGDMA and ethanol in the resin composition, as well as the type and caries activity of involved teeth. Resin infiltration has superior penetrability compared to fissure sealant, casein phosphopeptide-amorphous calcium phosphate nanocomplexes, flowable composite, adhesive and fluoride varnish. Resin penetration depth may be a critical factor in forming a diffusion barrier and the effectiveness of infiltration in halting the progression of caries.
树脂渗透及其渗透能力的研究正成为新兴牙科领域的焦点。树脂渗透深度可能是形成扩散屏障及渗透成功与否的关键决定因素。这篇综述文章的目的是评估市售树脂渗透剂在早期龋损中的渗透深度，并确定影响树脂渗透能力的因素。
在四个数据库（PubMed、Science Direct、Scopus和Web of Science）中进行文献检索，并于2009年至2022年12月进行人工检索。纳入标准包括与影响树脂渗透剂渗入牙釉质深度的因素相关的研究。采用研究报告清单（CRIS）进行偏倚风险评估。
初步检索共得到297项研究。对其中29项进行了资格评估，23项被选入定性综合分析。根据CRIS指南，所有研究均被归类为中度偏倚风险。树脂渗透受盐酸对牙釉质表面的处理、含二甲基丙烯酸三乙二醇酯（TEGDMA）的配方、乙醇的添加、渗透时间、渗透持续时间、唾液污染、龋活性及牙齿类型的影响。为了实现更好的树脂灌注，需要去除过度矿化的表层。
实现最佳树脂渗透的关键取决于盐酸对牙釉质的表面处理及应用技术、渗透持续时间、树脂组合物中TEGDMA和乙醇的配方，以及患牙的类型和龋活性。与窝沟封闭剂、酪蛋白磷酸肽 - 无定形磷酸钙纳米复合物、流动复合树脂、粘结剂和氟漆相比，树脂渗透具有更好的穿透性。树脂渗透深度可能是形成扩散屏障及阻止龋病进展的渗透有效性的关键因素。
