Mohajeri Gholamreza, Talebzadeh Hamid, Fallah-Mehrjardi Ali, Soltani Hamidreza, Neshan Mahdi
Department of Thoracic Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.
Resident of Thoracic Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2023 Jun 30;12:172. doi: 10.4103/abr.abr_198_22. eCollection 2023.
Spontaneous pneumothorax is a potentially fatal condition with a high risk of recurrence. The purpose of this study is to compare two different approaches to SP management. In the first group, patients underwent only chemical pleurodesis; in the second group, CT-scan, VATS, and then chemical pleurodesis was performed.
This study is a non-randomized clinical trial conducted on 65 patients admitted to Al-Zahra Hospital in Isfahan with a primary complaint of sudden dyspnea and a definitive diagnosis of spontaneous pneumothorax. Two studies compared the main outcomes of recurrence within six months and the time until recurrence.
Age, sex, and BMI were matched between the two study groups. The side of the pneumothorax, smoking history, and pulmonary disease history did not differ significantly ( > 0.05). Pneumothorax recurrence did not differ significantly between the two groups (: 0.477).
This study demonstrated no distinction between VATS and chemical pleurodesis when using only chemical pleurodesis. However, because numerous studies have suggested that one of these techniques may be beneficial for patients with SP, it is recommended to conduct additional randomized controlled trials (RCTs) with a more detailed plan and more comparable procedures, although it appears that meta-analysis design may be effective given the abundance of available RCT studies.
自发性气胸是一种具有潜在致命性且复发风险高的疾病。本研究的目的是比较两种不同的自发性气胸治疗方法。第一组患者仅接受化学性胸膜固定术；第二组患者先进行CT扫描、电视辅助胸腔镜手术（VATS），然后进行化学性胸膜固定术。
本研究是一项非随机临床试验，对65名因突发呼吸困难入院且确诊为自发性气胸的患者进行。两项研究比较了六个月内复发的主要结局以及复发时间。
两个研究组在年龄、性别和体重指数方面相匹配。气胸的侧别、吸烟史和肺部疾病史无显著差异（>0.05）。两组之间气胸复发情况无显著差异（：0.477）。
本研究表明，仅使用化学性胸膜固定术时，电视辅助胸腔镜手术（VATS）和化学性胸膜固定术之间没有区别。然而，由于众多研究表明这些技术之一可能对自发性气胸患者有益，建议进行更详细计划和更具可比性程序的额外随机对照试验（RCT），尽管鉴于现有大量随机对照试验研究，荟萃分析设计似乎可能有效。
