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日本大阪府新冠疫情期间住院困难患者的发病率及转归:一项基于人群的描述性研究

Incidence and outcome of patients with difficulty in hospital acceptance during COVID-19 pandemic in Osaka Prefecture, Japan: A population-based descriptive study.

作者信息

Katayama Yusuke, Tanaka Kenta, Kitamura Tetsuhisa, Dohmi Hisaya, Masui Jun, Hirose Tomoya, Nakao Shunichiro, Tachino Jotaro, Oda Jun, Matsuoka Tetsuya

机构信息

The Working Group to Analyse the Emergency Medical Care System in Osaka Prefecture Osaka Japan.

Department of Traumatology and Acute Critical Medicine Osaka University Graduate School of Medicine Suita Japan.

出版信息

Acute Med Surg. 2023 Aug 8;10(1):e880. doi: 10.1002/ams2.880. eCollection 2023 Jan-Dec.

Abstract

AIM

The impact of the coronavirus disease (COVID-19) pandemic on the emergency medical service system in Japan has not been fully revealed. The purpose of this study was to determine the impact of the COVID-19 pandemic in 2021 on the difficulty in hospital acceptance of patients and patient outcome in Osaka Prefecture.

METHODS

This study was a descriptive epidemiological study with a 3-year study period from January 2019 to December 2021. We included patients who were transported by ambulance and had registered in the Osaka Emergency Information Research Intelligent Operation Network (ORION) system. The primary end-point of this study was the difficulty in hospital acceptance by month, and the secondary outcome was the mortality of patients who experience difficulty in hospital acceptance in each year.

RESULTS

We included 1,302,646 cases in this study. The proportion of cases with difficulty in hospital acceptance was 2.74% (12,829/468,709) in 2019, 3.74% (15,527/414,987) in 2020, and 5.09% (21,311/418,950) in 2021. The crude odds ratio for 2020 was 1.38 (95% confidence interval, 1.35-1.41) and for 2021 was 1.90 (95% confidence interval, 1.86-1.95). In 2019, 218 patients with difficulty in hospital acceptance had died by 21 days after hospitalization, whereas the number increased to 405 in 2020 and 750 in 2021.

CONCLUSION

The number of patients experiencing difficulty in hospital acceptance during the COVID-19 pandemic in Osaka Prefecture increased, and patient outcomes were worse than before the pandemic.

摘要

目的

冠状病毒病(COVID-19)大流行对日本紧急医疗服务系统的影响尚未完全显现。本研究的目的是确定2021年COVID-19大流行对大阪府患者住院难及患者结局的影响。

方法

本研究为描述性流行病学研究,研究期为2019年1月至2021年12月的3年。我们纳入了由救护车转运并在大阪紧急信息研究智能运营网络(ORION)系统中登记的患者。本研究的主要终点是按月统计的住院难情况,次要结局是每年住院难患者的死亡率。

结果

本研究共纳入1,302,646例病例。2019年住院难病例的比例为2.74%(12,829/468,709),2020年为3.74%(15,527/414,987),2021年为5.09%(21,311/418,950)。2020年的粗比值比为1.38(95%置信区间,1.35 - 1.41),而2021年为1.90(95%置信区间,1.86 - 1.95)。2019年,218例住院难患者在住院后21天内死亡,而2020年这一数字增至405例,2021年增至750例。

结论

大阪府在COVID-19大流行期间住院难的患者数量增加,且患者结局比大流行前更差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4319/10410119/ba68092506ae/AMS2-10-e880-g002.jpg

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