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死产:预防与支持性哀伤护理

Stillbirth: prevention and supportive bereavement care.

作者信息

Atkins Bethany, Kindinger Lindsay, Mahindra Muhammad Pradhiki, Moatti Zoe, Siassakos Dimitrios

机构信息

Institute for Women's Health, University College London, London, UK.

National Institute for Health and Care Research, London, UK.

出版信息

BMJ Med. 2023 Jun 27;2(1):e000262. doi: 10.1136/bmjmed-2022-000262. eCollection 2023.

DOI:10.1136/bmjmed-2022-000262
PMID:37564829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10410959/
Abstract

Around half of the two million stillbirths occurring worldwide each year are preventable. This review compiles the most up-to-date evidence to inform stillbirth prevention. Many general maternal health interventions also reduce the risk of stillbirth, for example, antenatal care attendance. This review focuses on specific aspects of care: glucose metabolism, targeted aspirin prophylaxis, clotting and immune disorders, sleep positions, fetal movement monitoring, and preconception and interconception health. In the past few years, covid-19 infection during pregnancy has emerged as a risk factor for stillbirth, particularly among women who were not vaccinated. Alongside prevention, efforts to address stillbirth must include provision of high quality, supportive, and compassionate bereavement care to improve parents' wellbeing. A growing body of evidence suggests beneficial effects for parents who received supportive care and were offered choices such as mode of birth and the option to see and hold their baby. Staff need support to be able to care for parents effectively, yet, studies consistently highlight the scarcity of specific bereavement care training for healthcare providers. Action is urgently needed and is possible. Action must be taken with the evidence available now, in healthcare settings with high or low resources, to reduce stillbirths and improve training and care.

摘要

全球每年约有200万例死产,其中约一半是可以预防的。本综述汇集了最新证据,为死产预防提供参考。许多一般性的孕产妇保健干预措施也能降低死产风险,例如产前检查。本综述重点关注护理的具体方面:葡萄糖代谢、靶向阿司匹林预防、凝血和免疫紊乱、睡眠姿势、胎动监测以及孕前和孕间健康。在过去几年中,孕期感染新冠病毒已成为死产的一个风险因素,尤其是在未接种疫苗的女性中。除了预防措施,应对死产的努力还必须包括提供高质量、支持性和富有同情心的丧亲护理,以改善父母的福祉。越来越多的证据表明,接受支持性护理并能做出诸如分娩方式以及是否看望和抱抱婴儿选择的父母会从中受益。工作人员需要支持才能有效地照顾父母,然而,研究一直强调医疗保健提供者缺乏专门的丧亲护理培训。迫切需要且有可能采取行动。必须利用现有的证据,在资源丰富或匮乏的医疗环境中采取行动,以减少死产并改善培训和护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41d3/10410959/50979696934d/bmjmed-2022-000262f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41d3/10410959/50979696934d/bmjmed-2022-000262f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41d3/10410959/50979696934d/bmjmed-2022-000262f01.jpg

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本文引用的文献

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Chance of healthy versus adverse outcome in subsequent pregnancy after previous loss beyond 16 weeks: data from a specialized follow-up clinic.既往孕16周后流产的女性再次妊娠时出现健康结局与不良结局的几率:来自一家专业随访诊所的数据
J Matern Fetal Neonatal Med. 2023 Dec;36(1):2165062. doi: 10.1080/14767058.2023.2165062.
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Perinatal autopsy in Ghana: Healthcare workers knowledge and attitude.加纳的围产期尸检:医护人员的知识与态度。
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Pregnancy outcomes after SARS-CoV-2 infection in periods dominated by delta and omicron variants in Scotland: a population-based cohort study.
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Addressing Stillbirth: Exploring Economic Status, Government Strategies, and Gaps.应对死产:探索经济状况、政府策略及差距
Cureus. 2025 Jan 4;17(1):e76923. doi: 10.7759/cureus.76923. eCollection 2025 Jan.
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Prevention of Pregnancy Complications Using a Multimodal Lifestyle, Screening, and Medical Model.采用多模式生活方式、筛查和医学模式预防妊娠并发症
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The Contribution of Multiple Pregnancies in Stillbirths in Greece: A Time-Trend Analysis.希腊死产中多胎妊娠的贡献:一项时间趋势分析。
Cureus. 2024 Feb 21;16(2):e54628. doi: 10.7759/cureus.54628. eCollection 2024 Feb.
苏格兰地区德尔塔和奥密克戎变异株为主流行期间感染 SARS-CoV-2 后的妊娠结局:一项基于人群的队列研究。
Lancet Respir Med. 2022 Dec;10(12):1129-1136. doi: 10.1016/S2213-2600(22)00360-5. Epub 2022 Oct 7.
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Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis.妊娠期糖尿病与不良妊娠结局:系统评价与荟萃分析。
BMJ. 2022 May 25;377:e067946. doi: 10.1136/bmj-2021-067946.
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Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy.系统评价和荟萃分析 COVID-19 疫苗接种在妊娠中的有效性和围产期结局。
Nat Commun. 2022 May 10;13(1):2414. doi: 10.1038/s41467-022-30052-w.
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Abnormal placental villous maturity and dysregulated glucose metabolism: implications for stillbirth prevention.胎盘绒毛成熟异常与葡萄糖代谢失调:对死产预防的意义。
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