Alexandria University, High Institute of Public Health, Bab Sharqi, Egypt.
Alexandria University, Faculty of Medicine, Al Attarin, Egypt.
Medicine (Baltimore). 2023 Aug 11;102(32):e34777. doi: 10.1097/MD.0000000000034777.
There is a scarcity of studies focusing on irritable bowel syndrome (IBS) and anxiety in Egypt. Accordingly, our study aimed to assess the association between anxiety and IBS symptomatology among Egyptian females. Three hundred eighty-three females (145 IBS and 238 controls) were included in the study, and data were obtained using structured predesigned questionnaires. IBS and anxiety symptoms were assessed according to the Rome IV criteria and the Arabic version of the beck anxiety inventory, respectively. Both IBS and non-IBS groups showed increased anxiety during the pandemic, without a significant difference between both groups (P value = .657). Higher levels of education were significantly associated with severe anxiety (P value = .031). Multivariate analysis of IBS patients showed that intermediate education was significantly associated with 75% lower odds for increased IBS symptoms compared with illiterate or read-and-write IBS patients [odds ratio (OR): 0.25, 95% confidence interval (CI) 0.06-0.95, P value = .042]. Urban residence was significantly associated with 13.5 times greater odds of increased IBS symptoms, compared with rural residence (OR: 13.48, 95% CI 3.55-51.25, P value < .001). Moreover, patients who lost their job during the pandemic were 12.9 times more likely to have increased symptoms (OR: 12.89, 95% CI 1.84-90.15, P value = 0.01). A unit increase in patients age and beck anxiety inventory score was associated with 68% and 75% greater odds for increased IBS symptoms, respectively (OR: 1.68, 95% CI 1.12-2.53, P value = .012; OR: 1.75, 95% CI 1.08-2.84, P value = .024). Increasing anxiety is associated with increased IBS symptoms. Therefore, IBS patients should be screened for anxiety, and the role of psychiatric management of anxiety in the amelioration of IBS symptoms must be explored.
目前针对埃及肠易激综合征（IBS）和焦虑症的研究较少。因此，我们的研究旨在评估埃及女性中焦虑症与 IBS 症状之间的关联。研究纳入了 383 名女性（145 名 IBS 患者和 238 名对照者），并使用结构化预设计问卷获得数据。根据罗马 IV 标准和阿拉伯语版贝克焦虑量表评估 IBS 和焦虑症状。IBS 组和非 IBS 组在疫情期间都表现出焦虑增加，但两组之间没有显著差异（P 值=.657）。较高的教育水平与严重焦虑显著相关（P 值=.031）。对 IBS 患者进行多变量分析显示，与文盲或读写 IBS 患者相比，中等教育程度与 IBS 症状增加的可能性降低 75%显著相关[比值比（OR）：0.25，95%置信区间（CI）0.06-0.95，P 值=.042]。与农村居民相比，城市居民出现 IBS 症状增加的可能性高 13.5 倍（OR：13.48，95%CI 3.55-51.25，P 值<.001）。此外，在疫情期间失业的患者出现症状增加的可能性高 12.9 倍（OR：12.89，95%CI 1.84-90.15，P 值= 0.01）。患者年龄和贝克焦虑量表评分每增加 1 个单位，IBS 症状增加的可能性分别增加 68%和 75%（OR：1.68，95%CI 1.12-2.53，P 值=.012；OR：1.75，95%CI 1.08-2.84，P 值=.024）。焦虑增加与 IBS 症状增加相关。因此，IBS 患者应进行焦虑筛查，必须探索焦虑症的精神科管理在改善 IBS 症状中的作用。
