Department of Medical and Clinical Pharmacology, Centre of Pharmacovigilance and Pharmacoepidemiology, Faculty of Medicine, Toulouse University Hospital (CHU), Toulouse, France.
Eur J Clin Pharmacol. 2023 Oct;79(10):1375-1384. doi: 10.1007/s00228-023-03547-8. Epub 2023 Aug 11.
Recently, there has been a growing interest in using ChatGPT for various applications in Medicine. We evaluated the interest of OpenAI chatbot (GPT 4.0) for drug information activities at Toulouse Pharmacovigilance Center.
Based on a series of 50 randomly selected questions sent to our pharmacovigilance center by healthcare professionals or patients, we compared the level of responses from the chatbot GPT 4.0 with those provided by specialists in pharmacovigilance.
Chatbot answers were globally not acceptable. Responses to inquiries regarding the assessment of drug causality were not consistently precise or clinically meaningful.
The interest of chatbot assistance needs to be confirmed or rejected through further studies conducted in other pharmacovigilance centers.
最近,人们对使用 ChatGPT 应用于医学的各种领域产生了浓厚的兴趣。我们评估了 OpenAI 聊天机器人(GPT 4.0)在图卢兹药物警戒中心进行药物信息活动的兴趣。
基于向我们的药物警戒中心发送的由医疗保健专业人员或患者随机选择的 50 个问题,我们比较了聊天机器人 GPT 4.0 的回复水平与药物警戒专家提供的回复水平。
聊天机器人的回答总体上不能接受。对于药物因果关系评估的查询,回复并不总是准确或具有临床意义。
需要通过在其他药物警戒中心进行的进一步研究来确认或拒绝聊天机器人辅助的兴趣。