Vilariño Federico Matías Álvarez, Cheong Issac, Gómez Raúl Alejandro
Department of Critical Care Medicine, CABA, Sanatorio de Los Arcos, Juan B. Justo 909, Buenos Aires, Argentina.
Argentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.
J Ultrasound. 2023 Aug 11. doi: 10.1007/s40477-023-00814-3.
Minoxidil is a drug designed for the treatment of arterial hypotension. Due to its secondary effect of hypertrichosis, it is also used for alopecia treatment. We present a case of a 50-year-old female patient who was orally consuming Minoxidil for medical reasons. She presented with severe hypotension, requiring vasoactive drugs, and evidence of myocardial injury was detected using speckle tracking echocardiography. It is worth noting that the patient did not have any coronary heart disease, and the myocardial injury was found to be associated with Minoxidil consumption. Remarkably, the patient showed signs of reversal 72 h after stopping the drug. To our knowledge, this is the first reported case of subendocardial injury associated with Minoxidil, using speckle tracking echocardiography. In the resolution of the case, it was essential to rule out differential diagnoses, administer vasopressors, and use the speckle tracking echocardiography, which allowed for the objective assessment of myocardial injury and the monitoring of the patient during their hospitalization.
米诺地尔是一种用于治疗动脉低血压的药物。由于其多毛症的副作用，它也被用于治疗脱发。我们报告一例50岁女性患者，因医疗原因口服米诺地尔。她出现严重低血压，需要使用血管活性药物，并且通过斑点追踪超声心动图检测到心肌损伤的证据。值得注意的是，该患者没有任何冠心病，且发现心肌损伤与服用米诺地尔有关。值得注意的是，患者在停药72小时后出现好转迹象。据我们所知，这是第一例使用斑点追踪超声心动图报告的与米诺地尔相关的心内膜下损伤病例。在该病例的诊断过程中，排除鉴别诊断、使用血管升压药以及使用斑点追踪超声心动图至关重要，这使得能够对心肌损伤进行客观评估并在患者住院期间对其进行监测。
